INT104691

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Context Info
Confidence 0.06
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.69
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CXCL1) signal transduction (CXCL1) extracellular space (CXCL1)
extracellular region (CXCL1) intracellular (CXCL1)
CXCL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 30 100.00 Very High Very High Very High
cytokine 6 100.00 Very High Very High Very High
Inflammation 16 92.52 High High
cINOD 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cystic Fibrosis 30 100.00 Very High Very High Very High
INFLAMMATION 16 92.52 High High
Pseudomonas Infection 2 65.04 Quite High
Disease 4 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this work, we demonstrate the increased release of the proinflammatory cytokines after lipopolysaccharide (LPS) stimulation: human interleukin (hIL)-8 in CF and non-CF airway xenografts, and hIL-6 and human growth-related oncogene-alpha (hGRO-alpha), which could be only analyzed in non-CF xenografts.
Positive_regulation (stimulation) of Localization (release) of growth-related oncogene-alpha associated with fibrosis and cytokine
1) Confidence 0.06 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12183675 Disease Relevance 1.35 Pain Relevance 0.74
In this work, we demonstrate the increased release of the proinflammatory cytokines after lipopolysaccharide (LPS) stimulation: human interleukin (hIL)-8 in CF and non-CF airway xenografts, and hIL-6 and human growth-related oncogene-alpha (hGRO-alpha), which could be only analyzed in non-CF xenografts.
Positive_regulation (increased) of Localization (release) of growth-related oncogene-alpha associated with fibrosis and cytokine
2) Confidence 0.06 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12183675 Disease Relevance 1.35 Pain Relevance 0.74

General Comments

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