INT104696

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Context Info
Confidence 0.09
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.68
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CXCL1) signal transduction (CXCL1) extracellular space (CXCL1)
extracellular region (CXCL1) intracellular (CXCL1)
Anatomy Link Frequency
eosinophils 1
CXCL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 27 100.00 Very High Very High Very High
Inflammation 17 100.00 Very High Very High Very High
fibrosis 15 100.00 Very High Very High Very High
chemokine 3 100.00 Very High Very High Very High
cINOD 1 25.00 Low Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 100.00 Very High Very High Very High
Cystic Fibrosis 15 100.00 Very High Very High Very High
Adhesions 2 94.08 High High
Diabetes Mellitus 1 86.24 High High
Pseudomonas Infection 1 65.04 Quite High
Uremia 1 54.28 Quite High
Apoptosis 6 33.48 Quite Low
Disease 2 25.00 Low Low
Obesity 22 21.68 Low Low
Frailty 1 12.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this work, we demonstrate the increased release of the proinflammatory cytokines after lipopolysaccharide (LPS) stimulation: human interleukin (hIL)-8 in CF and non-CF airway xenografts, and hIL-6 and human growth-related oncogene-alpha (hGRO-alpha), which could be only analyzed in non-CF xenografts.
Localization (release) of growth-related oncogene-alpha associated with fibrosis and cytokine
1) Confidence 0.09 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12183675 Disease Relevance 1.35 Pain Relevance 0.74
Moreover, leptin could also stimulate the chemokinesis of eosinophils and induce the release of inflammatory cytokines IL-1beta and IL-6 and chemokines IL-8, growth-related oncogene-alpha, and MCP-1 [49].

2.3.

Localization (release) of growth-related oncogene-alpha in eosinophils associated with chemokine, inflammation and cytokine
2) Confidence 0.03 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.33 Pain Relevance 0.18

General Comments

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