INT104744

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Context Info
Confidence 0.53
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ugt1a1) enzyme binding (Ugt1a1)
Ugt1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 8 50.00 Quite Low
Inflammation 82 16.08 Low Low
Pain 1 10.00 Low Low
cytokine 14 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Periodontitis 60 100.00 Very High Very High Very High
Periodontal Disease 18 81.44 Quite High
Cancer 4 63.40 Quite High
Mouth Disease 2 56.88 Quite High
Alveolar Bone Loss 14 51.04 Quite High
Hypercalcemia 4 26.76 Quite Low
INFLAMMATION 88 16.08 Low Low
Disease 6 15.04 Low Low
Adhesions 12 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Five patients were homozygous for the UGT1A1 TA(7) allele, which is associated with reduced UGT1A1 gene expression.
Negative_regulation (reduced) of Gene_expression (expression) of UGT1A1 gene
1) Confidence 0.53 Published 2002 Journal Eur. J. Clin. Pharmacol. Section Body Doc Link 12185559 Disease Relevance 0.06 Pain Relevance 0
Treatment of rats with Hypericum significantly reduced the ligature-induced inhibition of Bcl-2 expression (Figure 7b, b1).
Negative_regulation (inhibition) of Gene_expression (expression) of b1
2) Confidence 0.08 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.40 Pain Relevance 0
Hypericum treatment significantly prevented the periodontitis-mediated NF-kB p65 expression (Figure 3b, b1).
Negative_regulation (prevented) of Gene_expression (expression) of b1 associated with periodontitis
3) Confidence 0.08 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.39 Pain Relevance 0

General Comments

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