INT104777

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Context Info
Confidence 0.38
First Reported 2002
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.38
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DES) cytoskeleton (DES) intracellular (DES)
cytoskeleton organization (DES) cytoplasm (DES)
Anatomy Link Frequency
muscles 2
neuronal 1
DES (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 50 100.00 Very High Very High Very High
Pain 34 100.00 Very High Very High Very High
acular 21 100.00 Very High Very High Very High
Eae 14 85.48 High High
cINOD 2 76.88 Quite High
nociceptor 4 65.04 Quite High
B1 receptor 17 55.36 Quite High
Antinociceptive 1 52.72 Quite High
antagonist 2 51.64 Quite High
Acute pain 1 50.00 Quite Low
Disease Link Frequency Relevance Heat
Injury 32 100.00 Very High Very High Very High
Cancer 41 99.04 Very High Very High Very High
Myalgia 8 98.24 Very High Very High Very High
Multiple Myeloma 1 93.88 High High
Pain 34 90.72 High High
Inflammatory Pain 13 85.48 High High
Disease 2 83.88 Quite High
Amputation 3 82.84 Quite High
Anastomotic Leak 1 74.08 Quite High
Alveolar Rhabdomyosarcoma 3 72.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In terms of biophysical modeling of DES responses, the experimental uncertainty summarized in Corollary 2.1, i.e., in a given experiment does DES target local neuronal populations or en passant fibers?
Regulation (populations) of DES in neuronal
1) Confidence 0.38 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2972750 Disease Relevance 0.05 Pain Relevance 0
In the present study, a high resolution immunocytochemical method was used to investigate the changes of desmin and actin in human muscles following a bout of eccentric exercise that lead to DOMS 2-3 days post-exercise.
Spec (investigate) Regulation (changes) of desmin in muscles associated with myalgia
2) Confidence 0.35 Published 2002 Journal Histochem. Cell Biol. Section Abstract Doc Link 12189520 Disease Relevance 0.35 Pain Relevance 0
Instead, the tumor cells showed striking CD99, synapthophysin and desmin immunoreactivity.
Regulation (immunoreactivity) of desmin associated with cancer
3) Confidence 0.26 Published 2010 Journal Mol Cytogenet Section Body Doc Link PMC2908072 Disease Relevance 1.00 Pain Relevance 0
Desmin and actin alterations in human muscles affected by delayed onset muscle soreness: a high resolution immunocytochemical study.
Regulation (alterations) of Desmin in muscles associated with pain and myalgia
4) Confidence 0.21 Published 2002 Journal Histochem. Cell Biol. Section Title Doc Link 12189520 Disease Relevance 0.32 Pain Relevance 0.10
Effect of tissue injury and ketorolac treatment on BK and des-Arg9-BK
Regulation (Effect) of des-Arg9-BK associated with injury, acular and bradykinin
5) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2834653 Disease Relevance 0.66 Pain Relevance 1.10

General Comments

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