INT104797

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smarce1, REST) DNA binding (Smarce1, REST) cytosol (REST)
nucleolus (REST) intracellular (REST) transcription factor binding (REST)
Anatomy Link Frequency
neuronal 1
Smarce1 (Mus musculus)
REST (Homo sapiens)
Pain Link Frequency Relevance Heat
Nav1.2 1 100.00 Very High Very High Very High
sodium channel 1 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Repression 4 88.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo, BAF57 occupies the neuronal sodium channel gene (Nav1.2) promoter, and targeting to this gene requires REST.
BAF57 Positive_regulation (requires) of REST in neuronal associated with nav1.2 and sodium channel
1) Confidence 0.01 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 12192000 Disease Relevance 0.24 Pain Relevance 0.15

General Comments

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