INT1048

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Context Info
Confidence 0.39
First Reported 1976
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 5
Total Number 8
Disease Relevance 0.37
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
HPC 2
dorsal 1
HPC 1
ventral 1
hpc (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 88 100.00 Very High Very High Very High
anesthesia 6 97.28 Very High Very High Very High
amygdala 10 75.00 Quite High
medulla 2 75.00 Quite High
midbrain 1 65.32 Quite High
Paracetamol 1 57.72 Quite High
local anesthetic 1 53.52 Quite High
monoamine 1 42.64 Quite Low
Nucleus accumbens 8 25.80 Quite Low
Anterior cingulate cortex 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 28 87.92 High High
Anxiety Disorder 40 79.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given that state in the HPC is dependent on variations in cholinergic tone in both sleep and under urethane anesthesia, in the present study we induced theta and SO states via systemic cholinergic manipulations in urethane-anesthetized rats to confirm similar changes in synaptic responsiveness.
Regulation (dependent) of HPC in HPC associated with anesthesia and hippocampus
1) Confidence 0.39 Published 2010 Journal Hippocampus Section Abstract Doc Link 19437417 Disease Relevance 0 Pain Relevance 0.28
HPC and HCTZ levels have little or no effect on the amount of HCTZ lost.
Neg (little) Regulation (effect) of HPC
2) Confidence 0.23 Published 2000 Journal Drug Dev Ind Pharm Section Abstract Doc Link 10738651 Disease Relevance 0 Pain Relevance 0.06
In all experiments, regardless of the anatomical locus or technique used to induce HPC theta, pre- and post-PH procaine comparisons of the PO and PH stimulation trials revealed that frequency modulation of HPC theta recovered significantly more slowly than amplitude. 3) Last is the effect of electrical stimulation of the PO and PH on HPC theta induced by carbachol infusions at the level of the HPC, MS, or PH.
Regulation (modulation) of HPC in HPC
3) Confidence 0.23 Published 1994 Journal Hippocampus Section Abstract Doc Link 7874237 Disease Relevance 0 Pain Relevance 0.09
Of course, it is possible that both dHPC and vHPC lesions affect performance on the intertemporal choice task, but for different reasons.
Spec (possible) Regulation (affect) of dHPC
4) Confidence 0.10 Published 2008 Journal Behav Neurosci Section Body Doc Link PMC2671844 Disease Relevance 0.09 Pain Relevance 0.04
An alternative explanation is that both the dorsal and ventral hippocampus contribute to temporal information processing, a suggestion which is also consistent with the effects of both dHPC and vHPC lesions on the nonspatial, DRL task.
Regulation (effects) of dHPC in dorsal associated with hippocampus
5) Confidence 0.10 Published 2008 Journal Behav Neurosci Section Body Doc Link PMC2671844 Disease Relevance 0.06 Pain Relevance 0.05
However, the effect of dHPC lesions on this task was not necessarily as predicted on the basis of the anatomical segregation of HPC-OFC connections.
Regulation (effect) of dHPC
6) Confidence 0.10 Published 2008 Journal Behav Neurosci Section Body Doc Link PMC2671844 Disease Relevance 0.16 Pain Relevance 0.08
The inhibitory effect of the HPC stimulation on the release of these hormones was also blocked by PCPA treatment.
Regulation (effect) of HPC in HPC associated with hippocampus
7) Confidence 0.04 Published 1976 Journal Endocrinol. Jpn. Section Abstract Doc Link 132346 Disease Relevance 0 Pain Relevance 0.49
An alternative explanation is that both the dorsal and ventral hippocampus contribute to temporal information processing, a suggestion which is also consistent with the effects of both dHPC and vHPC lesions on the nonspatial, DRL task.
Regulation (effects) of dHPC in ventral associated with hippocampus
8) Confidence 0.03 Published 2008 Journal Behav Neurosci Section Body Doc Link PMC2671844 Disease Relevance 0.06 Pain Relevance 0.05

General Comments

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