INT104837

Context Info Confidence 0.00 First Reported 2002 Last Reported 2002 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.15

cell differentiation (GLI2) cell proliferation (GLI2) nucleus (GLI2) intracellular (GLI2) cilium (GLI2) cytoplasm (GLI2)

Anatomy Link Frequency THP-1 1 IGKV2OR2-1 (Homo sapiens) GLI2 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 3 99.20 Opioid 1 63.36

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These results suggest that endomorphins 1 and 2 may inhibit THP-1 functions, such as cytokine production and functions related to innate immune, and potentiate NF-kappaB DNA binding in THP-1.

endomorphins 1 and 2 Spec (may) Negative_regulation (inhibit) of THP-1 in THP-1 associated with cytokine

1) Confidence 0.00 Published 2002 Journal Scand. J. Immunol. Section Abstract Doc Link 12193227 Disease Relevance 0 Pain Relevance 0.15

General Comments

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