INT10485

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Context Info
Confidence 0.11
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.21
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (STMN1) signal transduction (STMN1) cytoskeleton (STMN1)
intracellular (STMN1) cytoplasm (STMN1) signal transducer activity (STMN1)
Anatomy Link Frequency
eyes 1
NAc 1
frontal cortex 1
STMN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 4 99.66 Very High Very High Very High
cocaine 4 98.44 Very High Very High Very High
Morphine 11 95.48 Very High Very High Very High
Nucleus accumbens 3 94.88 High High
antidepressant 3 75.00 Quite High
opioid receptor 1 69.60 Quite High
nMDA receptor 1 25.00 Low Low
anesthesia 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 4 99.84 Very High Very High Very High
Glaucoma 91 99.16 Very High Very High Very High
Ganglion Cysts 23 88.00 High High
Familial Adenomatous Polyposis 4 32.08 Quite Low
Ocular Hypertension 18 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low
Hypertension 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Scotoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the retina, STMN immunoreactivity was very low in normal eyes (Figure 4A).
Regulation (immunoreactivity) of STMN in eyes
1) Confidence 0.11 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567987 Disease Relevance 0.98 Pain Relevance 0
We identified one heavily regulated phosphoprotein in frontal cortex as the 32-kDa dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32).
Regulation (regulated) of phosphoprotein in frontal cortex associated with dopamine and urological neuroanatomy
2) Confidence 0.00 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1494903 Disease Relevance 0.23 Pain Relevance 0.12
Cocaine-sensitized rats showed increased phosphorylation of dopamine- and cyclic AMP-regulated phosphoprotein Mr 32 kDa (DARPP-32) at threonine-75 (Thr75) and decreased DARPP-32 phosphorylation at Thr34, in the caudate-putamen (CPu) and nucleus accumbens (NAc) 7 days after sensitization assessment.
Regulation (regulated) of phosphoprotein in NAc associated with nucleus accumbens, dopamine and cocaine
3) Confidence 0.00 Published 2004 Journal J. Neurochem. Section Abstract Doc Link 15287884 Disease Relevance 0 Pain Relevance 0.83

General Comments

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