INT104945

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Context Info
Confidence 0.60
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
AGS 2
DYT10 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 93.76 High High
COX-2 inhibitor 4 80.04 Quite High
Kinase C 1 75.00 Quite High
cINOD 2 59.12 Quite High
Disease Link Frequency Relevance Heat
Alagille Syndrome 2 99.48 Very High Very High Very High
Stomach Cancer 5 91.60 High High
Apoptosis 6 90.88 High High
Gastrointestinal Neoplasms 1 60.92 Quite High
INFLAMMATION 1 58.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SC-236 down-regulated the protein expression and kinase activity of PKC-beta(1), increased the expression of PKCdelta and PKCeta, but did not alter the expression of other PKC isoforms in AGS cells.
Neg (not) Regulation (alter) of Gene_expression (expression) of PKC in AGS associated with alagille syndrome
1) Confidence 0.60 Published 2002 Journal Oncogene Section Abstract Doc Link 12203123 Disease Relevance 0.85 Pain Relevance 0.28

General Comments

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