INT104972

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Context Info
Confidence 0.20
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.35
Pain Relevance 1.45

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protein complex assembly (MITF) DNA binding (MITF) protein complex (MITF)
cytoplasm (TYR) cell proliferation (TYR) pigmentation (TYR)
MITF (Homo sapiens)
TYR (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 18 95.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Microphthalmia 4 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The microphthalmia-associated transcription factor (MITF), which belongs to the family of bHLH-LZ type transcription factors, regulates the transcription of melanogenesis-related enzyme genes such as the tyrosinase and TRP-1 genes.
MITF Regulation (regulates) of Transcription (transcription) of tyrosinase associated with microphthalmia
1) Confidence 0.20 Published 2002 Journal Life Sci. Section Abstract Doc Link 12204775 Disease Relevance 0.17 Pain Relevance 0.72
The microphthalmia-associated transcription factor (MITF), which belongs to the family of bHLH-LZ type transcription factors, regulates the transcription of melanogenesis-related enzyme genes such as the tyrosinase and TRP-1 genes.
microphthalmia-associated transcription factor Regulation (regulates) of Transcription (transcription) of tyrosinase associated with microphthalmia
2) Confidence 0.20 Published 2002 Journal Life Sci. Section Abstract Doc Link 12204775 Disease Relevance 0.17 Pain Relevance 0.73

General Comments

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