INT104989

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) plasma membrane (Prkaca) nucleus (Prkaca)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 94.76 High High
Sciatic nerve 1 87.44 High High
Abeta 2 86.96 High High
Hyperalgesia 1 85.52 High High
Morphine 2 50.00 Quite Low
Inflammation 1 48.24 Quite Low
cytokine 1 47.20 Quite Low
Pain 1 31.76 Quite Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 94.76 High High
Hyperalgesia 1 85.52 High High
Skin Allergy 1 81.00 Quite High
Necrosis 2 78.28 Quite High
Cancer 2 77.92 Quite High
INFLAMMATION 1 48.24 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
Hemorrhagic Shock 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: Studies were conducted in five groups of urethane-anesthetized Sprague-Dawley rats: Group 1--control group, Group 2--a non-receptor-blocking adenylate cyclase inhibitor: SQ22536, at 100 microg/kg (n = 5), Group 3--a PKA inhibitor: H89, at 10 microg/kg, Group 4--a morphine sulfate (10 microg/kg) and PKA inhibitor group, and Group 5--an adenylate cyclase inhibited and morphine (10 microg/kg) group.
Positive_regulation (conducted) of Negative_regulation (inhibitor) of PKA
1) Confidence 0.33 Published 2008 Journal Anesth. Analg. Section Body Doc Link 18227303 Disease Relevance 0 Pain Relevance 0
Alternatively, H-89 or Rp-cAMPS, two specific cAMP-dependent protein kinase (PKA) inhibitors, was added to the perfusion solution for 15 min prior to TNF-alpha application.
Positive_regulation (added) of Negative_regulation (inhibitors) of PKA
2) Confidence 0.10 Published 2002 Journal J. Neurophysiol. Section Abstract Doc Link 12205159 Disease Relevance 0.81 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox