INT105026

Context Info Confidence 0.37 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0

mitochondrion (Pars2) ligase activity (Pars2) cytoplasm (Pars2)

Anatomy Link Frequency diaphragm 2 Pars2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat anesthesia 1 46.32

Disease Link Frequency Relevance Heat Endotoxemia 2 92.84 Sepsis 2 92.60 Pressure And Volume Under Development 1 25.00 Injury 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In our experimental study, the effects of poly(ADP-ribose) synthetase (PARS) inhibition on the diaphragmatic Ca(2+)-ATPase, malondialdehyde (MDA), and 3-nitrotyrosine (3-NT) levels and additionally histopathology of the diaphragm in lipopolysaccharide (LPS)-induced endotoxemia are investigated.Thirty-two male Wistar rats, weighing between 180-200 g were randomly divided into four groups.

Regulation (effects) of Negative_regulation (inhibition) of PARS in diaphragm associated with endotoxemia

1) Confidence 0.37 Published 2002 Journal Pharmacol. Res. Section Abstract Doc Link 12208123 Disease Relevance 0.19 Pain Relevance 0

General Comments

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