INT105106

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Plat, NFKB1) extracellular space (Plat, Cxcl12) extracellular region (Plat, Cxcl12)
nucleoplasm (NFKB1) mitochondrion (NFKB1) cytosol (NFKB1)
Anatomy Link Frequency
skin 2
Plat (Mus musculus)
Cxcl12 (Mus musculus)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 7 98.36 Very High Very High Very High
Inflammation 1 93.04 High High
Disease Link Frequency Relevance Heat
Cancer 2 100.00 Very High Very High Very High
Nociception 1 93.88 High High
INFLAMMATION 1 93.04 High High
Leukemia 2 75.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies from this laboratory revealed that capsaicin, when topically applied onto dorsal skin of female ICR mice, strongly attenuated activation of NF-kappaB and AP-1 induced by the typical tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), which may account for its anti-tumor promoting activity in mouse skin.
TPA Positive_regulation (induced) of 12-O-tetradecanoylphorbol-13-acetate Positive_regulation (activation) of NF-kappaB in skin associated with qutenza and cancer
1) Confidence 0.01 Published 2002 Journal Arch. Pharm. Res. Section Abstract Doc Link 12214859 Disease Relevance 0.54 Pain Relevance 0.53

General Comments

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