INT105131

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Context Info
Confidence 0.58
First Reported 2002
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 8
Total Number 12
Disease Relevance 9.10
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

KRT122P (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 17 98.16 Very High Very High Very High
Inflammation 7 89.04 High High
abdominal pain 2 87.56 High High
ischemia 1 77.72 Quite High
tolerance 8 75.28 Quite High
corticosteroid 1 72.08 Quite High
agonist 18 51.12 Quite High
Pain 12 36.36 Quite Low
headache 2 19.44 Low Low
chemokine 4 18.64 Low Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 2 100.00 Very High Very High Very High
Hepatitis C Virus Infection 1 100.00 Very High Very High Very High
Hepatitis A Virus Infection 1 99.64 Very High Very High Very High
Epstein-barr Virus 4 99.36 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 238 99.10 Very High Very High Very High
Phobia 30 98.48 Very High Very High Very High
Aseptic Necrosis Of Bone 27 98.36 Very High Very High Very High
Thalassemia 2 97.84 Very High Very High Very High
Targeted Disruption 22 97.76 Very High Very High Very High
Malaria 49 96.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-HAV IgM, HbsAg, anti-HBc IgM, anti-HCV and anti-CMV IgM were negative, while IgM VCA EBV, IgG VCA EBV and anti-CMV IgG were positive.
Neg (negative) Gene_expression (negative) of HBc associated with epstein-barr virus, cytomegalovirus infection, hepatitis c virus infection and hepatitis a virus infection
1) Confidence 0.58 Published 2002 Journal J. Infect. Section Abstract Doc Link 12217711 Disease Relevance 2.13 Pain Relevance 0.12
The incidence of osteonecrosis is also high in patients with hemoglobin SC (compound heterozygotes for HbS- and HbC-producing alleles: SC) and in the various types of sickle-beta-thalassemia (SThal) population.
Gene_expression (producing) of HbC associated with aseptic necrosis of bone and thalassemia
2) Confidence 0.58 Published 2008 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2687112 Disease Relevance 1.29 Pain Relevance 0.04
To be able to identify barriers to seeking ART, we enrolled two groups of subjects: (1) clients of one or more home-based AIDS care programmes; and (2) patients on ART at the HIV clinics serving the same populations as the HBC programmes.
Gene_expression (programmes) of HBC associated with acquired immune deficiency syndrome or hiv infection
3) Confidence 0.50 Published 2010 Journal J Int AIDS Soc Section Body Doc Link PMC2847987 Disease Relevance 0.66 Pain Relevance 0.13
South African HBC organizations received structured questionnaires; key informant interviews and a literature review were completed to assess systems for production, distribution and supply of HBC kits.
Gene_expression (production) of HBC
4) Confidence 0.49 Published 2008 Journal AIDS Care Section Abstract Doc Link 18608083 Disease Relevance 0.15 Pain Relevance 0.07
Thus, by working with HBC programmes to enrol HBC patients, we were able to select a sample of ill patients who had chosen not to initiate ART.
Gene_expression (programmes) of HBC
5) Confidence 0.43 Published 2010 Journal J Int AIDS Soc Section Body Doc Link PMC2847987 Disease Relevance 0.47 Pain Relevance 0.10
The one important exception to this was that we observed a somewhat greater association between being in the HBC group versus the ART group in terms of reported fear of abuse when we compared only females (RR female HBC vs. female ART: 1.82; 95% CI: 1.27-2.61) versus when we compared only males (RR male HBC vs. male ART: 1.40; 95% CI: 0.80-2.45).
Gene_expression (group) of HBC associated with phobia
6) Confidence 0.43 Published 2010 Journal J Int AIDS Soc Section Body Doc Link PMC2847987 Disease Relevance 0.23 Pain Relevance 0
We excluded all HBC subjects who were on ART, as well as subjects who had received ARVs prior to study enrolment.
Gene_expression (subjects) of HBC
7) Confidence 0.43 Published 2010 Journal J Int AIDS Soc Section Body Doc Link PMC2847987 Disease Relevance 0.50 Pain Relevance 0.09
Fear of attending the clinic was very common (Table 3) in all locations, with more HBC subjects than ART subjects reporting being afraid to go to the clinic (RR: 3.61; 95% CI: 2.80-4.66) and that if they went to the clinic, people would not like them (RR: 2.28; 95% CI: 1.82-2.87).
Gene_expression (subjects) of HBC associated with phobia
8) Confidence 0.43 Published 2010 Journal J Int AIDS Soc Section Body Doc Link PMC2847987 Disease Relevance 0.18 Pain Relevance 0
The most prevalent polymorphic variants of the HbB gene consist of the normal gene (HbA) in which SNPs in the same amino acid position give rise to either the sickle haemoglobin S, (HbS, Glu to Val at c6 (E6V)) or the common west-African haemoglobin C (HbC, Glu to Lys at c6 (E6K)).
Gene_expression (consist) of HbC
9) Confidence 0.10 Published 2005 Journal Malar J Section Body Doc Link PMC1326224 Disease Relevance 0.63 Pain Relevance 0.04
Anti-ICC-1132, anti-HBc and anti-(T1B)4 IgG1 and IgG3 subtypes, typical of TH1-type immune responses, developed preferentially over IgG2 and IgG4 subtypes (P?
Gene_expression (subtypes) of HBc
10) Confidence 0.06 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2216688 Disease Relevance 0.31 Pain Relevance 0
HspBCor-primed CTL lysed both peptide-pulsed and HBc-transfected target cells, which express HBc endogenously.
Gene_expression (express) of HBc
11) Confidence 0.04 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 1.28 Pain Relevance 0.06
HspBCor-primed CTL lysed both peptide-pulsed and HBc-transfected target cells, which express HBc endogenously.
Gene_expression (transfected) of HBc
12) Confidence 0.04 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 1.27 Pain Relevance 0.04

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