INT105142

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.08
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HSPB1) cell death (HSPB1) plasma membrane (HSPB1)
cytoskeleton (HSPB1) nucleus (HSPB1) intracellular (HSPB1)
HSPB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Snapping jaw 4 78.80 Quite High
Osteoarthritis 54 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
Inflammation 16 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 8 100.00 Very High Very High Very High
Metaplasia 2 97.40 Very High Very High Very High
Temporomandibular Joint Disorders 2 79.20 Quite High
Temporomandibular Joint Syndrome 2 75.00 Quite High
Stress 20 57.40 Quite High
Osteoarthritis 54 5.00 Very Low Very Low Very Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HSP27 was weakly expressed in normal TMJ discs and highly up-regulated in discs of patients showing new vessel formation and chondroid metaplasia.
Positive_regulation (up-regulated) of HSP27 associated with metaplasia
1) Confidence 0.70 Published 2002 Journal J Craniofac Surg Section Abstract Doc Link 12218804 Disease Relevance 0.50 Pain Relevance 0.15
Any correlation between gender and HSP27 was found in the sample, being the up-regulation of HSP27 related mostly to major histopathological changes.
Positive_regulation (up-regulation) of HSP27
2) Confidence 0.70 Published 2002 Journal J Craniofac Surg Section Abstract Doc Link 12218804 Disease Relevance 0.37 Pain Relevance 0.14
Interestingly, some of these proteins, such as heat shock protein beta-1 (HSPB1) or alpha enolase (ENOA) were present in more than one spot, indicating that they undergo posttranslational modifications, such as glycosylation or phosphorylation.
Positive_regulation (present) of heat shock protein beta-1 associated with shock
3) Confidence 0.43 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.10 Pain Relevance 0
Interestingly, some of these proteins, such as heat shock protein beta-1 (HSPB1) or alpha enolase (ENOA) were present in more than one spot, indicating that they undergo posttranslational modifications, such as glycosylation or phosphorylation.
Positive_regulation (present) of HSPB1 associated with shock
4) Confidence 0.43 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945029 Disease Relevance 0.10 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox