INT105149

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Context Info
Confidence 0.75
First Reported 2002
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 10
Total Number 15
Disease Relevance 12.27
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PTBP1) mRNA processing (PTBP1) nucleolus (PTBP1)
RNA binding (PTBP1) nucleus (PTBP1)
Anatomy Link Frequency
sweat 3
neurons 2
chest 1
socket 1
PTBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nucleus accumbens 16 99.58 Very High Very High Very High
Inflammation 11 98.78 Very High Very High Very High
Angina 12 97.92 Very High Very High Very High
cocaine 3 86.20 High High
cva 13 69.12 Quite High
Pain 24 64.92 Quite High
opioid receptor 2 64.68 Quite High
projection neuron 2 41.36 Quite Low
antagonist 2 37.96 Quite Low
agonist 8 32.48 Quite Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 690 100.00 Very High Very High Very High
Premature Birth 291 100.00 Very High Very High Very High
Cough 42 99.92 Very High Very High Very High
Fever 18 99.62 Very High Very High Very High
Disease 259 99.20 Very High Very High Very High
INFLAMMATION 13 98.78 Very High Very High Very High
Pre-term Labor 62 98.60 Very High Very High Very High
Angina 12 97.92 Very High Very High Very High
Anorexia 6 97.80 Very High Very High Very High
Weight Loss 6 97.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The clustered localization of PPTB-expressing neurons in the Acb and near absence of PPTB-expressing neurons in the dense cell layer of the OT suggests that neurokinin B is a key substance in differentiating between the ventral and dorsal striatal regions.
Gene_expression (expressing) of PPTB in neurons associated with nucleus accumbens
1) Confidence 0.75 Published 2002 Journal Neuroscience Section Abstract Doc Link 12220564 Disease Relevance 0 Pain Relevance 0.25
The clustered localization of PPTB-expressing neurons in the Acb and near absence of PPTB-expressing neurons in the dense cell layer of the OT suggests that neurokinin B is a key substance in differentiating between the ventral and dorsal striatal regions.
Gene_expression (expressing) of PPTB in neurons associated with nucleus accumbens
2) Confidence 0.75 Published 2002 Journal Neuroscience Section Abstract Doc Link 12220564 Disease Relevance 0 Pain Relevance 0.26
Overall knowledge of the study participants about PTB was assessed using the following 8 main questions: (1) able to mention bacteria/germ as a cause of PTB, (2) able to mention correct sign/symptoms of PTB (persistent cough for three or more weeks, sputum with blood, chest pain, weight loss, loss of appetite and fever/sweat), (3) able to classify PTB as a transmissible disease, (4) able to enumerate correct mode of transmission of PTB (cough/breath, sharing cups, not sharing feeding materials, not through body contact or sharing cloths), (5) knowing that PTB is treatable, (6) knowing that effective treatment for PTB is modern drug, (7) knowing that PTB is preventable, and (8) able to enumerate correct preventive methods of PTB (avoiding sharing cups, using separate room, early treatment).
Gene_expression (cause) of PTB in sweat associated with mycobacterial infection, angina, weight loss, anorexia, cough, disease and fever
3) Confidence 0.67 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 1.63 Pain Relevance 0.10
However, only 2 participants mentioned that bacteria/germs were the cause of PTB.
Gene_expression (cause) of PTB associated with mycobacterial infection
4) Confidence 0.67 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 0.88 Pain Relevance 0
Overall knowledge of the study participants about PTB was assessed using the following 8 main questions: (1) able to mention bacteria/germ as a cause of PTB, (2) able to mention correct sign/symptoms of PTB (persistent cough for three or more weeks, sputum with blood, chest pain, weight loss, loss of appetite and fever/sweat), (3) able to classify PTB as a transmissible disease, (4) able to enumerate correct mode of transmission of PTB (cough/breath, sharing cups, not sharing feeding materials, not through body contact or sharing cloths), (5) knowing that PTB is treatable, (6) knowing that effective treatment for PTB is modern drug, (7) knowing that PTB is preventable, and (8) able to enumerate correct preventive methods of PTB (avoiding sharing cups, using separate room, early treatment).
Gene_expression (transmission) of PTB in sweat associated with mycobacterial infection, angina, weight loss, anorexia, cough, disease and fever
5) Confidence 0.67 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 1.69 Pain Relevance 0.10
Overall knowledge of the study participants about PTB was assessed using the following 8 main questions: (1) able to mention bacteria/germ as a cause of PTB, (2) able to mention correct sign/symptoms of PTB (persistent cough for three or more weeks, sputum with blood, chest pain, weight loss, loss of appetite and fever/sweat), (3) able to classify PTB as a transmissible disease, (4) able to enumerate correct mode of transmission of PTB (cough/breath, sharing cups, not sharing feeding materials, not through body contact or sharing cloths), (5) knowing that PTB is treatable, (6) knowing that effective treatment for PTB is modern drug, (7) knowing that PTB is preventable, and (8) able to enumerate correct preventive methods of PTB (avoiding sharing cups, using separate room, early treatment).
Neg (preventable) Gene_expression (preventable) of PTB in sweat associated with mycobacterial infection, angina, weight loss, anorexia, cough, disease and fever
6) Confidence 0.67 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 1.71 Pain Relevance 0.09
Out of the 818 participants, 782 (95.6%) reported that they had heard about PTB (known locally as "Labadore") mainly from friends or PTB patients.
Gene_expression (heard) of PTB associated with mycobacterial infection
7) Confidence 0.67 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 0.78 Pain Relevance 0
It was also found that the pressure magnitude in hydrostatic socket is relatively lower than that of PTB socket.
Gene_expression (socket) of PTB in socket
8) Confidence 0.65 Published 2009 Journal Acta Bioeng Biomech Section Abstract Doc Link 20405814 Disease Relevance 0 Pain Relevance 0.06
This might be due to the fact that people may not suspect that early symptoms (coughing, fever and sweating) are due to PTB, unless accompanied by other severe symptoms (e.g. chest pain or hemoptysis) [24].
Gene_expression (due) of PTB in chest associated with mycobacterial infection, angina, hemoptysis and fever
9) Confidence 0.59 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2867998 Disease Relevance 1.10 Pain Relevance 0.10
Attempts to understand rates of PTD in lower socioeconomic groups have not yet yielded benefit in terms of providing clues to the cause of PTB in general.30 Furthermore, attempts at intervention by improvement of social support mechanisms in this population have neither resulted in a decrease in the rates of PTD nor in improvement in outcome by any perinatal measures.34,35
Gene_expression (cause) of PTB associated with premature birth
10) Confidence 0.39 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697509 Disease Relevance 1.01 Pain Relevance 0.04
Different concentrations of siRNA that target PTB were first reverse-transfected into Huh7 cells cultured in a 384-well plate and followed by DENV infection at a multiplicity of infection (MOI) of 1.
Gene_expression (transfected) of PTB associated with infection
11) Confidence 0.34 Published 2010 Journal Virol J Section Body Doc Link PMC2825209 Disease Relevance 0.69 Pain Relevance 0
We found that the rates of spontaneous PTB were significantly higher in those with ?
Gene_expression (spontaneous) of PTB associated with premature birth
12) Confidence 0.34 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697509 Disease Relevance 0.85 Pain Relevance 0
In a multinational double blind placebo controlled trial on the use of bioadhesive progesterone vaginal gel for the prevention of PTB in 611 women,106 the findings revealed no significant differences between the progesterone vaginal gel and placebo in the rate of PTB at <35 weeks’ gestation (Table 1).
Neg (prevention) Gene_expression (prevention) of PTB associated with premature birth
13) Confidence 0.34 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2697509 Disease Relevance 0.86 Pain Relevance 0
Preterm Birth in Caucasians Is Associated with Coagulation and Inflammation Pathway Gene Variants

Spontaneous preterm birth (<37 weeks gestation—PTB) occurs in ?

Gene_expression (gestation) of PTB associated with inflammation and premature birth
14) Confidence 0.31 Published 2008 Journal PLoS ONE Section Title Doc Link PMC2553267 Disease Relevance 0.46 Pain Relevance 0.08
Accurate prediction of PTB in women admitted with threatened preterm labor remains difficult.
Gene_expression (prediction) of PTB associated with pre-term labor
15) Confidence 0.17 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2861440 Disease Relevance 0.62 Pain Relevance 0

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