INT105240

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2002
Last Reported 2002
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.18
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (POMC, CXCL10) extracellular space (POMC, CXCL10) signal transduction (POMC, CXCL10)
extracellular region (POMC, CXCL10) small molecule metabolic process (POMC) cytoplasm (POMC)
Anatomy Link Frequency
keratinocytes 3
monocytes 1
POMC (Homo sapiens)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 100.00 Very High Very High Very High
tolerance 2 100.00 Very High Very High Very High
Inflammation 2 100.00 Very High Very High Very High
Nerve growth factor 2 92.12 High High
c fibre 2 89.52 High High
Neuropeptide 8 88.24 High High
substance P 2 84.56 Quite High
Calcitonin gene-related peptide 6 80.00 Quite High
Disease Link Frequency Relevance Heat
Contact Dermatitis 4 100.00 Very High Very High Very High
INFLAMMATION 2 100.00 Very High Very High Very High
Necrosis 2 75.68 Quite High
Cancer 2 75.32 Quite High
Skin Cancer 2 55.72 Quite High
Wrinkles 2 54.28 Quite High
Burns 2 53.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The POMC product alpha-melanocyte-stimulating hormone (alpha-MSH) has been implicated in suppression of contact hypersensitivity and induction of hapten-specific tolerance, most likely by inducing keratinocytes and monocytes to produce the anti-inflammatory cytokine IL-10.
POMC product alpha-melanocyte-stimulating hormone Spec (likely) Positive_regulation (inducing) of Gene_expression (produce) of cytokine IL-10 in keratinocytes associated with inflammation, tolerance, contact dermatitis and cytokine
1) Confidence 0.07 Published 2002 Journal Methods Section Abstract Doc Link 12231193 Disease Relevance 0.59 Pain Relevance 0.58
The POMC product alpha-melanocyte-stimulating hormone (alpha-MSH) has been implicated in suppression of contact hypersensitivity and induction of hapten-specific tolerance, most likely by inducing keratinocytes and monocytes to produce the anti-inflammatory cytokine IL-10.
POMC product alpha-melanocyte-stimulating hormone Spec (likely) Positive_regulation (inducing) of in monocytes Gene_expression (produce) of cytokine IL-10 in keratinocytes associated with inflammation, tolerance, contact dermatitis and cytokine
2) Confidence 0.02 Published 2002 Journal Methods Section Abstract Doc Link 12231193 Disease Relevance 0.59 Pain Relevance 0.58

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox