INT105343

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Context Info
Confidence 0.39
First Reported 2002
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gck) nucleoplasm (Gck) mitochondrion (Gck)
nucleus (Gck) carbohydrate metabolic process (Gck) kinase activity (Gck)
Anatomy Link Frequency
melanocyte 2
Gck (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid 5 100.00 Very High Very High Very High
Cannabinoid receptor 3 100.00 Very High Very High Very High
agonist 1 80.12 Quite High
cannabis 1 75.84 Quite High
Analgesic 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genes affected similarly by Delta(9)-THC and R(+)-WIN 55,212-2 were considered likely to reflect cannabinoid receptor activation, and expression of the protein products of two such genes not previously implicated in cannabinoid signaling-melanocyte-specific gene-related gene 1 (MRG1) and hexokinase 4 (glucokinase, GK)-was measured by Western blotting and immunohistochemistry.
Spec (likely) Negative_regulation (reflect) of Gene_expression (expression) of glucokinase in melanocyte associated with cannabinoid receptor and cannabinoid
1) Confidence 0.39 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 12237329 Disease Relevance 0 Pain Relevance 0.36

General Comments

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