INT105436

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Context Info
Confidence 0.08
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, CPOX) cytosol (IRF6) mitochondrion (CPOX)
small molecule metabolic process (CPOX) oxidoreductase activity (CPOX) nucleus (IRF6)
Anatomy Link Frequency
plaque 1
IRF6 (Homo sapiens)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 98.76 Very High Very High Very High
Abeta 2 61.84 Quite High
COX2 1 25.00 Low Low
COX-2 inhibitor 1 25.00 Low Low
cOX1 1 25.00 Low Low
cINOD 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Disease 6 99.60 Very High Very High Very High
Cancer 1 96.72 Very High Very High Very High
Necrosis 1 96.48 Very High Very High Very High
Alzheimer's Dementia 1 95.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COX-2 immunoreactivity and mRNA were induced by lipopolysaccharide (LPS), not by AD plaque associated cytokines interleukin (IL)-1alpha, IL-1beta, IL-6, tumor necrosis factor (TNF)-alpha, or amyloid (A)beta(1-42).
LPS Neg (not) Positive_regulation (induced) of COX in plaque associated with necrosis, cancer, alzheimer's dementia, disease and cytokine
1) Confidence 0.08 Published 2002 Journal Brain Res. Section Abstract Doc Link 12270500 Disease Relevance 0.74 Pain Relevance 0.11

General Comments

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