INT10553

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Context Info
Confidence 0.15
First Reported 1992
Last Reported 2008
Negated 0
Speculated 2
Reported most in Abstract
Documents 13
Total Number 16
Disease Relevance 2.12
Pain Relevance 3.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GPER) endoplasmic reticulum (GPER) plasma membrane (GPER)
signal transducer activity (GPER)
Anatomy Link Frequency
blood 9
sympathetic 2
skull 1
neutrophil 1
GPER (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 14 99.84 Very High Very High Very High
Enkephalin 8 99.84 Very High Very High Very High
medulla 3 99.44 Very High Very High Very High
qutenza 12 99.18 Very High Very High Very High
Angina 1 98.68 Very High Very High Very High
Migraine 4 98.28 Very High Very High Very High
Serotonin 2 98.20 Very High Very High Very High
cva 5 97.84 Very High Very High Very High
ketamine 1 97.52 Very High Very High Very High
Calcitonin gene-related peptide 6 96.96 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 3 99.20 Very High Very High Very High
Stable Angina Pectoris 1 98.96 Very High Very High Very High
Increased Venous Pressure Under Development 4 98.60 Very High Very High Very High
Headache 4 98.28 Very High Very High Very High
Hemorrhage 3 97.84 Very High Very High Very High
Endolymphatic Hydrops 4 88.16 High High
INFLAMMATION 19 87.76 High High
Targeted Disruption 7 87.12 High High
Hypertension 1 86.28 High High
Salivary Gland Disease 2 84.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our analysis of the genes closest to MER85 elements (Table S4) suggests that the CSB-PGBD3 fusion protein may have created just such a regulatory network based on MER85 elements.
Regulation (based) of MER85
1) Confidence 0.15 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2268245 Disease Relevance 0.05 Pain Relevance 0
Regulatory Patterns among MER85-Associated Genes
Regulation (Regulatory) of MER85
2) Confidence 0.15 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2268245 Disease Relevance 0 Pain Relevance 0
Moreover, if the PGBD3 domain of the fusion protein targets CSB-dependent chromatin remodeling complexes to MER85 elements, loss of CSB might affect regulation of MER85-associated genes (Tables S4, S5, S6, S7) or enable MER85 elements themselves to sequester chromatin remodeling factors.


Spec (might) Regulation (regulation) of MER85
3) Confidence 0.10 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2268245 Disease Relevance 0 Pain Relevance 0
Nonetheless, even in the absence of an effect of feG on neutrophil CD11b obtained from OA-challenged animals, the observed change in CD16 suggests that the IgG-receptor is an important participant in feG regulation of neutrophil function after exposure to allergen.


Regulation (regulation) of feG in neutrophil
4) Confidence 0.02 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.35 Pain Relevance 0.13
Dynamic changes in pulpal blood flow (PBF) elicited by electrical stimulation, pinching, heating, and capsaicin application to the gingivae were investigated in cat mandibular canine teeth by means of Laser Doppler Velocimetry.
Spec (investigated) Regulation (changes) of pulpal blood flow in blood associated with qutenza
5) Confidence 0.01 Published 1994 Journal J. Dent. Res. Section Abstract Doc Link 7814750 Disease Relevance 0.07 Pain Relevance 0.23
PURPOSE: The present study tested the hypothesis that the anesthetic technique will influence the changes in regional blood flow (RBF) during intraoperative cardiac tamponade.
Regulation (changes) of regional blood flow in blood associated with cv unclassified under development
6) Confidence 0.01 Published 2004 Journal Can J Anaesth Section Abstract Doc Link 15574553 Disease Relevance 0.17 Pain Relevance 0.07
After 5-12 days, a laser-Doppler flow (LDF) probe was attached to the skull by means of a guiding device to measure changes in brain cortical blood flow (CBF).
Regulation (changes) of cortical blood flow in skull
7) Confidence 0.00 Published 2005 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15894567 Disease Relevance 0.17 Pain Relevance 0.14
The role of renal sympathetic nerve activity (RSNA) in the physiological regulation of medullary blood flow (MBF) remains ill defined, yet regulation of MBF may be crucial to long-term arterial pressure regulation.
Regulation (regulation) of medullary blood flow in sympathetic
8) Confidence 0.00 Published 2001 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 11124135 Disease Relevance 0.14 Pain Relevance 0
Although certain studies have reported evoked changes in cochlear blood flow (CBF) with activation of the sympathetic fibers to the cochlear vasculature, other studies have failed to show evidence of sympathetic contribution to CBF regulation when the cervical sympathetic fibers were unilaterally sectioned.
Regulation (changes) of cochlear blood flow in sympathetic
9) Confidence 0.00 Published 1997 Journal Hear. Res. Section Abstract Doc Link 9083811 Disease Relevance 0 Pain Relevance 0.05
Changes in forearm blood flow (FBF) during intrabrachial infusion of: (i) serotonin (releasing endogenous NO), (ii) sodium nitroprusside (SNP, exogenous NO-donor), and (iii) CGRP were measured using venous occlusion plethysmography.
Regulation (Changes) of forearm blood flow in blood associated with serotonin and calcitonin gene-related peptide
10) Confidence 0.00 Published 2006 Journal Cephalalgia Section Abstract Doc Link 16396667 Disease Relevance 0.17 Pain Relevance 0.46
The present investigation examines the relationship between the capsaicin-sensitive sensory neurons and SP in the regulation of cochlear blood flow (CBF).
Regulation (regulation) of cochlear blood flow in blood associated with qutenza and substance p
11) Confidence 0.00 Published 1995 Journal Hear. Res. Section Abstract Doc Link 8600135 Disease Relevance 0 Pain Relevance 0.93
The role of adrenal medulla-derived enkephalins in the control of hypercapnic cerebrocortical blood flow (CBF) and oxygen consumption (CMRO2) was investigated in the ketamine anesthetized rat.
Regulation (control) of cerebrocortical blood flow in blood associated with medulla, ketamine and enkephalin
12) Confidence 0.00 Published 1992 Journal Brain Res. Section Abstract Doc Link 1504767 Disease Relevance 0.14 Pain Relevance 0.69
Effect of mean platelet volume on postintervention coronary blood flow in patients with chronic stable angina pectoris.
Regulation (Effect) of coronary blood flow in blood associated with stable angina pectoris and angina
13) Confidence 0.00 Published 2008 Journal J Invasive Cardiol Section Title Doc Link 18316827 Disease Relevance 0.10 Pain Relevance 0.10
Autoregulation of cochlear blood flow in the hydropic guinea pig.
Regulation (Autoregulation) of cochlear blood flow in blood
14) Confidence 0.00 Published 1995 Journal Hear. Res. Section Title Doc Link 8600117 Disease Relevance 0.17 Pain Relevance 0
Previous data suggest that regulation of cochlear blood flow (CBF) may be abnormal in the hydropic guinea pig.
Regulation (regulation) of cochlear blood flow in blood
15) Confidence 0.00 Published 1995 Journal Hear. Res. Section Abstract Doc Link 8600117 Disease Relevance 0.16 Pain Relevance 0
Our objective was to compare the effects on central hemodynamics and carotid blood flow of two hemoglobin solutions after resuscitation from hemorrhage in anesthetized guinea pigs.
Regulation (effects) of carotid blood flow in blood associated with cva
16) Confidence 0.00 Published 1999 Journal Artif Cells Blood Substit Immobil Biotechnol Section Abstract Doc Link 10063438 Disease Relevance 0.42 Pain Relevance 0.21

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