INT105543

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 4.63
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (DNTT) nucleus (DNTT) intracellular (DNTT)
DNA binding (DNTT) cytoplasm (DNTT)
Anatomy Link Frequency
Embryos 1
tails 1
epithelial cells 1
parenchyma 1
DNTT (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 3 98.68 Very High Very High Very High
gABA 3 98.56 Very High Very High Very High
cytokine 22 98.24 Very High Very High Very High
Etanercept 26 92.96 High High
Neurotransmitter 5 92.88 High High
Inflammation 74 90.68 High High
Hyperalgesia 1 85.76 High High
Arthritis 1 75.00 Quite High
Glutamate receptor 2 71.20 Quite High
dexamethasone 2 69.52 Quite High
Disease Link Frequency Relevance Heat
Cancer 112 99.76 Very High Very High Very High
Anxiety Disorder 209 99.42 Very High Very High Very High
Hematological Disease 1 99.08 Very High Very High Very High
Apoptosis 185 99.02 Very High Very High Very High
Death 116 98.80 Very High Very High Very High
Rheumatoid Arthritis 3 98.68 Very High Very High Very High
Diabetes Mellitus 80 95.68 Very High Very High Very High
Body Weight 2 94.44 High High
Leukemia 4 91.60 High High
Disease 17 91.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Apoptotic cells in colonic epithelial cells were detected using the terminal deoxynucleotidyl transferase (TdT)-mediated free 3'-OH end labeling (TUNEL) assay (ApopTaq In Situ Apoptosis Detection Kit; Chemicon, Temecula, CA), following the manufacturer's instructions.
Gene_expression (using) of TdT in epithelial cells associated with apoptosis
1) Confidence 0.65 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2912804 Disease Relevance 0.41 Pain Relevance 0.03
Ki67 immunostaining and TdT-mediated dUTP nick-end labelling
Gene_expression (immunostaining) of TdT
2) Confidence 0.65 Published 2006 Journal Virchows Arch Section Body Doc Link PMC1888720 Disease Relevance 0.70 Pain Relevance 0
DNA fragmentation was detected by TUNEL (TdT-mediated dUTP Nick-End Labeling; DeadEnd Fluorometric TUNEL system, Promega) following the manufacturer's protocol.
Gene_expression (detected) of TdT
3) Confidence 0.65 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2072952 Disease Relevance 0.09 Pain Relevance 0.03
Terminal transferase dUTP nick end labeling (TUNEL) staining
Gene_expression (staining) of Terminal transferase
4) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2211395 Disease Relevance 0.48 Pain Relevance 0.19
Tissue immunohistochemical-staining and terminal transferase-mediated dUTP nick-end labeling assay
Gene_expression (staining) of terminal transferase
5) Confidence 0.65 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2223071 Disease Relevance 0 Pain Relevance 0
PolyA tails were added to fragmented genomic DNA using terminal transferase (TdT) as follows: 1.5 µg of DNA fragments were incubated for 30 min at 37°C in a total reaction volume of 50 µl containing 40 U TdT (New England BioLabs.), CoCl2 0.25 mM, and dATP 0.4 mM.
Gene_expression (using) of TdT in tails
6) Confidence 0.65 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2698986 Disease Relevance 0 Pain Relevance 0
Terminal transferase dUTP nick end labeling and M30 staining
Gene_expression (end) of Terminal transferase
7) Confidence 0.65 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2716944 Disease Relevance 0.36 Pain Relevance 0.08
Embryos were rehydrated through an ethanol series and sequentially washed with PBS, PBST (0.2% Tween 20 in PBS), and terminal deoxynucleotidyl transferase (TdT) buffer (Invitrogen).
Gene_expression (washed) of TdT in Embryos
8) Confidence 0.65 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2813296 Disease Relevance 0 Pain Relevance 0
The tumor cells were positive for CD19 and cytoplasmatic IgM as well as CD10, CD34 and TdT consistent with ALL.
Gene_expression (positive) of TdT associated with cancer
9) Confidence 0.26 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2853499 Disease Relevance 0.97 Pain Relevance 0.09
Zai et al.92 investigated five polymorphisms in the GABA type B receptor 1 (GABBR1) gene in 159 OCD probands and their families using the TDT, and they found a trend with an over-transmission of the -7265A allele at the A-7265G polymorphism in OCD.
Gene_expression (using) of TDT associated with gaba and anxiety disorder
10) Confidence 0.04 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687723 Disease Relevance 1.00 Pain Relevance 0.32
Here, in an animal model of rheumatoid arthritis, we show that microsomal prostaglandin E-synthase, the inducible terminal isomerase in the prostaglandin E(2)-synthesizing pathway, is expressed in endothelial cells along the blood-brain barrier and in the parenchyma of the paraventricular hypothalamic nucleus.
Gene_expression (expressed) of terminal isomerase in parenchyma associated with rheumatoid arthritis
11) Confidence 0.00 Published 2002 Journal J. Comp. Neurol. Section Abstract Doc Link 12353217 Disease Relevance 0.61 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox