INT105571

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Context Info
Confidence 0.58
First Reported 2002
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 33
Total Number 33
Disease Relevance 14.68
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SRGN) extracellular region (SRGN) Golgi apparatus (SRGN)
Anatomy Link Frequency
lens 3
eye 2
blood 1
plasma 1
cardiovascular system 1
SRGN (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 21 97.80 Very High Very High Very High
agonist 199 94.28 High High
antagonist 114 91.52 High High
imagery 10 91.44 High High
Dopamine 131 90.48 High High
Serotonin 14 89.96 High High
Pain 4 85.84 High High
Inflammation 6 81.36 Quite High
isoflurane 28 66.80 Quite High
depression 29 52.36 Quite High
Disease Link Frequency Relevance Heat
Glaucoma 102 100.00 Very High Very High Very High
Hyperglycemia 50 100.00 Very High Very High Very High
Pyoderma Gangrenosum 6 100.00 Very High Very High Very High
Myopia 968 99.84 Very High Very High Very High
Myocardial Infarction 36 99.72 Very High Very High Very High
Hypoglycemia 510 99.68 Very High Very High Very High
Crohn's Disease 1 99.68 Very High Very High Very High
Optic Disorders 32 99.40 Very High Very High Very High
Stroke 16 99.14 Very High Very High Very High
Disease 56 98.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aortic pressure and PPG were simultaneously recorded in 10 dogs under general anesthesia during changes in atrioventricular (AV) delay and bursts of rapid pacing to simulate tachyarrhythmias.
Gene_expression (pressure) of PPG associated with heart rate under development and anesthesia
1) Confidence 0.58 Published 2008 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 18849335 Disease Relevance 0.17 Pain Relevance 0.10
Our patient had no signs of active Crohn disease at the time of PPG presentation.
Gene_expression (presentation) of PPG associated with crohn's disease and pyoderma gangrenosum
2) Confidence 0.57 Published 2002 Journal Am Surg Section Abstract Doc Link 12356159 Disease Relevance 1.38 Pain Relevance 0.16
Low-frequency fluctuation in the cardiac cycle is mainly controlled by the sympathetic nerve.23 Variation in blood flow (IA and IS) is generated due to vasoconstriction and vasodilation, both of which are significantly affected by the sympathetic nervous system.24 Therefore, PPG signal specifically provides information regarding blood volume as well as that on blood pumping and its transportation status.5 The IT component is used in studies that measure blood volume, while the IS component validates the existence of resistance in studies on the vascular compliance with the cardiovascular system, such as hypertension.25
Gene_expression (signal) of PPG in blood associated with cv unclassified under development and increased venous pressure under development
3) Confidence 0.56 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0.34 Pain Relevance 0
The change in the cardiovascular system due to cardiac stimulants, such as a change in IBP and the PPG components, was detected and analyzed by the presented animal experiments.
Gene_expression (change) of PPG in cardiovascular system
4) Confidence 0.49 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0.06 Pain Relevance 0.04
The changes in the IBP, HR, and PPG components were expressed as means with standard deviations.
Gene_expression (expressed) of PPG
5) Confidence 0.44 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0 Pain Relevance 0.07
Based on these five points, a revised diagnostic approach of glaucoma at the preperimetric stage is considered such that the subjective clinical diagnosis of GON as the reference standard in diagnosing PPG would probably be changed by adopting the available and more accurate alternative: objective and quantitative assessment of the peripapillary RNFL thickness loss.
Gene_expression (diagnosing) of PPG associated with glaucoma and optic disorders
6) Confidence 0.44 Published 2010 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2928913 Disease Relevance 1.10 Pain Relevance 0.04
The aforementioned PPG studies used OCT-3 or GDx-VCC [2, 3, 9, 16].
Gene_expression (studies) of PPG associated with glaucoma
7) Confidence 0.44 Published 2010 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2928913 Disease Relevance 0.40 Pain Relevance 0.09
When OADs no longer adequately control PPG excursions, prandial insulin can be added at mealtimes, one meal at a time, to a simple basal insulin regimen.
Gene_expression (excursions) of PPG
8) Confidence 0.28 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2515417 Disease Relevance 0.38 Pain Relevance 0
After 12 weeks, the mean daily PPG increment was significantly lower with biphasic insulin aspart compared to biphasic human insulin (difference between groups ?
Gene_expression (increment) of PPG
9) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.55 Pain Relevance 0
If however, the biphasic insulin aspart was injected 15 minutes after the start of a meal, the PPG profile was comparable to biphasic human insulin (Kapitza et al 2004).
Gene_expression (profile) of PPG
10) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.28 Pain Relevance 0
As large epidemiologic studies suggest that PPG levels correlate better with adverse cardiovascular outcomes and death, one potential advantage of biphasic insulin aspart is better PPG control.
Gene_expression (levels) of PPG associated with death
11) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.37 Pain Relevance 0
Significantly fewer PPG excursions were observed after biphasic insulin aspart 70/30 compared to after biphasic insulin lispro 75/25 and to after biphasic human insulin 70/30, which suggests that biphasic insulin aspart more effectively reduces PPG compared to other biphasic insulins (Figure 2).
Gene_expression (excursions) of PPG
12) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.34 Pain Relevance 0
Conventional basal-bolus therapy, consisting of three daily injections of rapid- or short-acting insulin at every meal and one or two additional basal insulin injections, target both PPG and fasting plasma glucose; however they are not always practical as they require multiple daily injections.
Gene_expression (acting) of PPG in plasma
13) Confidence 0.26 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350128 Disease Relevance 0.44 Pain Relevance 0
In addition, AACE/ACE recommends the use of DPP-4 inhibitors vs other oral agents in patients when HbA1c is in the range of 6.5%–7.5% and FPG and PPG levels are elevated.1



Gene_expression (levels) of PPG
14) Confidence 0.25 Published 2010 Journal Core Evidence Section Body Doc Link PMC2963920 Disease Relevance 0.07 Pain Relevance 0
The expression of PPG was significantly down-regulated to below the levels seen in both contralateral control (t-test; p<0.05) and age-matched untreated eyes (t-test; p<0.05) after one day of lens wear.
Gene_expression (expression) of PPG in eyes
15) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.19 Pain Relevance 0
The primers used for the analysis of chicken ZENK and PPG RNA transcript expression, as well as ?
Gene_expression (expression) of PPG RNA transcript
16) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0 Pain Relevance 0
However, after one day of diffuser wear, PPG expression was significantly down-regulated (t-test, p<0.05), and remained so for the duration of the form-deprivation period (t-test; 3 days p<0.05, 7 days p<0.01, and 10 days p<0.05).
Gene_expression (expression) of PPG
17) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.27 Pain Relevance 0
For statistical analyses and graphical representation of changes in ZENK and PPG RNA transcript expression, the mean normalized expression (MNE) of the target genes was calculated separately for each condition (treated, contralateral control, and age-matched untreated control retinal tissue).
Gene_expression (expression) of PPG RNA transcript
18) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.07 Pain Relevance 0.03
In this paper, we show that the molecular changes in expression of ZENK and PPG are similar in FDM and LIM, and that both FDM and LIM appear to produce similar changes in retinal circuitry that increase the sensitivity of retinal circuits to dopaminergic agonists and muscarinic cholinergic antagonists within 1 h of the commencement of visual manipulation.
Gene_expression (expression) of PPG associated with antagonist, myopia and agonist
19) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.56 Pain Relevance 0.40
There was no significant difference over time in the expression of PPG transcript levels between contralateral control eyes, in either form-deprived animals or negative-lens-treated animals, and age-matched untreated values (MANOVA; F (2,86)=0.27, p=0.62 and F (2,86)=0.10, p=0.84, respectively).
Gene_expression (expression) of PPG in lens
20) Confidence 0.22 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.17 Pain Relevance 0

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