INT105618

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Context Info
Confidence 0.27
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 5.62
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (SEPHS1)
Anatomy Link Frequency
thyroid 1
SPs 1
SEPHS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 4 100.00 Very High Very High Very High
gABA 8 95.72 Very High Very High Very High
imagery 11 93.20 High High
Pain 12 93.04 High High
Central nervous system 2 80.48 Quite High
Neurotransmitter 2 79.28 Quite High
Abeta 4 77.92 Quite High
cINOD 3 57.92 Quite High
headache 10 5.00 Very Low Very Low Very Low
Migraine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stiff-person Syndrome 76 100.00 Very High Very High Very High
Depression 5 100.00 Very High Very High Very High
Amyloid Plaque 4 100.00 Very High Very High Very High
Disease 14 99.52 Very High Very High Very High
Diabetes Mellitus-type I 6 98.52 Very High Very High Very High
Diabetes Mellitus 6 96.12 Very High Very High Very High
Generalized Anxiety Disorder 24 95.24 Very High Very High Very High
Epilepsy 2 94.96 High High
Pain 11 93.04 High High
Alzheimer's Dementia 1 92.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to one study [4], IDDM is the most thoroughly documented condition, observed in 25% of patients presenting with SPS.
SPS Binding (presenting) of associated with diabetes mellitus-type i and stiff-person syndrome
1) Confidence 0.27 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2868875 Disease Relevance 1.55 Pain Relevance 0.21
The clinical associations of SPS with other disease processes have been observed, including thyroid disorders, insulin-dependent diabetes mellitus (IDDM) and epilepsy.
SPS Binding (associations) of in thyroid associated with epilepsy, diabetes mellitus-type i, diabetes mellitus, disease and stiff-person syndrome
2) Confidence 0.26 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2868875 Disease Relevance 1.57 Pain Relevance 0.21
FDDNP and its analogs have excellent ability to bind to NFTs and SPs in vitro as shown by binding assays, confocal fluorescence microscopy with stained AD brain tissue and digital autoradiography with [18F]FDDNP. [18F]FDDNP-PET molecular imaging permits detection of these pathologies in living subjects.
SPs Binding (bind) of in SPs associated with disease, imagery and amyloid plaque
3) Confidence 0.18 Published 2003 Journal Mol Imaging Biol Section Abstract Doc Link 14667495 Disease Relevance 0.93 Pain Relevance 0.23
The association between depression and QoL highlights the importance of recognizing and treating depression in SPS.
SPS Binding (recognizing) of associated with depression and stiff-person syndrome
4) Confidence 0.12 Published 2002 Journal Mov. Disord. Section Abstract Doc Link 12360560 Disease Relevance 1.31 Pain Relevance 0.23
Six months after surgery, patients completed the BPI-SF and SPS.
SPS Binding (completed) of
5) Confidence 0.08 Published 2004 Journal J Surg Orthop Adv Section Abstract Doc Link 15691180 Disease Relevance 0.26 Pain Relevance 0.26

General Comments

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