INT105624

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Context Info
Confidence 0.52
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.81
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd63) protein complex (Cd63) lysosome (Cd63)
cytoplasm (Cd63)
Anatomy Link Frequency
skin 1
platelets 1
basophil 1
PMN 1
Cd63 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 3 100.00 Very High Very High Very High
Enkephalin 6 99.86 Very High Very High Very High
Angina 3 95.72 Very High Very High Very High
Opioid 4 91.28 High High
IPN 2 85.52 High High
opioid receptor 1 83.56 Quite High
Pain 1 70.08 Quite High
Inflammation 1 64.72 Quite High
Percutaneous transluminal coronary angioplasty 4 26.08 Quite Low
anesthesia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 3 100.00 Very High Very High Very High
Anaphylaxis 8 99.16 Very High Very High Very High
Urological Neuroanatomy 1 99.12 Very High Very High Very High
Myocardial Infarction 9 97.84 Very High Very High Very High
Cv General 3 Under Development 3 95.72 Very High Very High Very High
Inflammatory Pain 2 85.52 High High
Pain 1 70.08 Quite High
INFLAMMATION 1 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We performed flow cytometric analysis of the expression on the cell surface of the basophil activation markers CD63 and CD203c and measured histamine release in 21 patients who were referred with possible peri-operative anaphylaxis.
Localization (release) of CD63 in basophil associated with anaphylaxis
1) Confidence 0.52 Published 2005 Journal Anaesthesia Section Abstract Doc Link 15710010 Disease Relevance 0.34 Pain Relevance 0
The sensitivity of CD63, CD203c, basophil histamine release and skin prick for the muscle relaxants was found to be 79%, 36%, 36% and 64%, respectively; the specificity was found to be 100%.
Localization (release) of CD63 in skin
2) Confidence 0.52 Published 2005 Journal Anaesthesia Section Abstract Doc Link 15710010 Disease Relevance 0.33 Pain Relevance 0
Using double immunofluorescence confocal microscopy, we showed that beta-endorphin (END) and Met-enkephalin (ENK) were colocalized with the primary (azurophil) granule markers CD63 and myeloperoxidase (MPO) within PMN.
Localization (colocalized) of CD63 in PMN associated with urological neuroanatomy and enkephalin
3) Confidence 0.52 Published 2007 Journal Brain Behav. Immun. Section Abstract Doc Link 17604950 Disease Relevance 0.32 Pain Relevance 0.96
The levels of platelet-derived microparticles (PDMPs), platelet activation markers (P-selectin, CD63, and PAC-1 on activated platelets), and C-C chemokines (monocyte chemotactic peptide [MCP]-1 and regulated on activation normally T-cell expressed and secreted [RANTES] were measured and compared in patients with acute myocardial infarction (AMI) or stable pectoris angina.
Localization (secreted) of CD63 in platelets associated with chemokine, heart rate under development, angina and myocardial infarction
4) Confidence 0.06 Published 2002 Journal Clin. Appl. Thromb. Hemost. Section Abstract Doc Link 12361207 Disease Relevance 0.82 Pain Relevance 0.25

General Comments

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