INT105934

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Context Info
Confidence 0.00
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (APTX) cell death (APTX) nucleolus (APTX)
nucleus (APTX) intracellular (APTX)
Anatomy Link Frequency
blood 2
APTX (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 4 98.00 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs [acyloxyalkoxy-based cyclic prodrug of DADLE (AOA-DADLE), coumarinic acid-based cyclic prodrug of DADLE (CA-DALE), and oxymethyl-modified coumarinic acid-based cyclic prodrug of DADLE (OMCA-DADLE)] across the blood-brain barrier (BBB) were determined using an in situ perfused rat brain model.
Gene_expression (prodrug) of AOA-DADLE in blood associated with opioid
1) Confidence 0.00 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12388672 Disease Relevance 0 Pain Relevance 0.17
The permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs [acyloxyalkoxy-based cyclic prodrug of DADLE (AOA-DADLE), coumarinic acid-based cyclic prodrug of DADLE (CA-DALE), and oxymethyl-modified coumarinic acid-based cyclic prodrug of DADLE (OMCA-DADLE)] across the blood-brain barrier (BBB) were determined using an in situ perfused rat brain model.
Gene_expression (prodrug) of AOA-DADLE in blood associated with opioid
2) Confidence 0.00 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12388672 Disease Relevance 0 Pain Relevance 0.17

General Comments

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