INT105936

Context Info Confidence 0.00 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.07

nucleoplasm (APTX) cell death (APTX) nucleolus (APTX) nucleus (APTX) intracellular (APTX)

APTX (Homo sapiens)

Pain Link Frequency Relevance Heat Opioid 2 75.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inclusion of GF-120918 (10 microM) in the perfusates fully inhibited the P-gp activity in the BBB and dramatically increased the P(app) values of AOA-DADLE, CA-DADLE, and OMCA-DADLE by approximately 50-, 460-, and 170-fold, respectively.

Regulation (values) of AOA-DADLE

1) Confidence 0.00 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12388672 Disease Relevance 0 Pain Relevance 0.07

General Comments

This test has worked.