INT105971

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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1, Ghrl) extracellular region (GH1, Ghrl) cytoplasm (Ghrl)
Anatomy Link Frequency
pituitary 2
GH1 (Homo sapiens)
Ghrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 8 85.48 High High
agonist 2 83.60 Quite High
Clonidine 2 82.00 Quite High
Disease Link Frequency Relevance Heat
Aging 10 97.92 Very High Very High Very High
Cardiovascular Disorder Under Development 2 5.00 Very Low Very Low Very Low
Reprotox - General 2 2 5.00 Very Low Very Low Very Low
Appetite Loss 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Discovery of GH secretagogues (GHSs), a series of peptydil and non-peptydil synthetic molecules endowed with a strong GH-releasing activity, the cloning of a GHS receptor (GHS-R), present in the hypothalamus and the pituitary, the isolation of the endogenous ligand of GHS-R, ghrelin, a 28-amino acid peptide whose main source is the stomach, pose the issue for the physiologic role of the GHS/ghrelin system and forces revision of our current understanding of GH regulation in different GH deficiency (GHD) states, including aging.
GH Regulation (regulation) of ghrelin in pituitary associated with aging
1) Confidence 0.03 Published 2002 Journal Neurobiol. Aging Section Abstract Doc Link 12392795 Disease Relevance 0.37 Pain Relevance 0.25
Discovery of GH secretagogues (GHSs), a series of peptydil and non-peptydil synthetic molecules endowed with a strong GH-releasing activity, the cloning of a GHS receptor (GHS-R), present in the hypothalamus and the pituitary, the isolation of the endogenous ligand of GHS-R, ghrelin, a 28-amino acid peptide whose main source is the stomach, pose the issue for the physiologic role of the GHS/ghrelin system and forces revision of our current understanding of GH regulation in different GH deficiency (GHD) states, including aging.
GH Regulation (regulation) of ghrelin in pituitary associated with aging
2) Confidence 0.03 Published 2002 Journal Neurobiol. Aging Section Abstract Doc Link 12392795 Disease Relevance 0.38 Pain Relevance 0.27

General Comments

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