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Context Info
Confidence 0.23
First Reported 2002
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.50
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PLAUR, VTN) extracellular matrix organization (VTN) enzyme binding (PLAUR)
signal transduction (PLAUR) extracellular space (VTN) proteinaceous extracellular matrix (VTN)
Anatomy Link Frequency
monocyte 1
PC-3 1
PLAUR (Homo sapiens)
VTN (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 9 99.38 Very High Very High Very High
Angina 1 76.48 Quite High
cINOD 1 75.20 Quite High
Inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Adhesions 15 100.00 Very High Very High Very High
Prostate Cancer 4 96.44 Very High Very High Very High
Myocardial Infarction 9 93.04 High High
Metastasis 3 83.84 Quite High
Pancreatic Cancer 1 78.80 Quite High
Cv General 3 Under Development 1 76.48 Quite High
INFLAMMATION 2 74.96 Quite High
Cancer 3 72.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Altogether, our data suggests that aspirin inhibits the formation of uPA-uPAR-FN-alpha3beta1 and uPA-uPAR-VN-alphavbeta3 complexes, resulting in the suppression of cell adhesion and cell motility of the highly invasive prostate cancer cells PC-3.
uPAR Binding (complexes) of VN in PC-3 associated with aspirin, prostate cancer and adhesions
1) Confidence 0.23 Published 2003 Journal Int. J. Oncol. Section Abstract Doc Link 14532966 Disease Relevance 0.82 Pain Relevance 0.37
The urokinase receptor (urokinase plasminogen activator receptor; uPAR) regulates monocyte adhesion by direct binding to vitronectin and by forming complexes with integrins.
uPAR Binding (binding) of vitronectin in monocyte associated with adhesions
2) Confidence 0.12 Published 2002 Journal Blood Section Abstract Doc Link 12393744 Disease Relevance 0.69 Pain Relevance 0.08

General Comments

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