INT106005

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Context Info
Confidence 0.59
First Reported 2002
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 2.66
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PLAUR) extracellular region (PLAUR) plasma membrane (PLAUR)
enzyme binding (PLAUR)
Anatomy Link Frequency
fibroblasts 4
monocytes 2
PLAUR (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 10 100.00 Very High Very High Very High
cINOD 3 74.96 Quite High
Angina 1 43.88 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 100.00 Very High Very High Very High
Myocardial Infarction 9 100.00 Very High Very High Very High
Necrosis 3 100.00 Very High Very High Very High
Cancer 3 100.00 Very High Very High Very High
Peptic Ulcer 3 99.88 Very High Very High Very High
Adhesions 11 99.28 Very High Very High Very High
Cv General 3 Under Development 1 43.88 Quite Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of indomethacin on uPA and uPAR expression in these cells was also examined.
Regulation (effect) of Gene_expression (expression) of uPAR
1) Confidence 0.59 Published 2003 Journal Dig. Dis. Sci. Section Abstract Doc Link 14714609 Disease Relevance 0.50 Pain Relevance 0.10
In conclusion, we found that uPAR expression is elevated on monocytes in AMI and contributes to enhanced cell adhesion.
Regulation (contributes) of Gene_expression (expression) of uPAR in monocytes associated with adhesions and myocardial infarction
2) Confidence 0.40 Published 2002 Journal Blood Section Abstract Doc Link 12393744 Disease Relevance 1.21 Pain Relevance 0.05
To clarify the role of human gastric fibroblasts in acute inflammatory conditions such as gastric ulcer, the effects of interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha on the expression of uPA and uPAR, which were suggested to be associated with tissue remodeling, in gastric fibroblasts were investigated.
Regulation (effects) of Gene_expression (expression) of uPAR in fibroblasts associated with necrosis, inflammation, cancer and peptic ulcer
3) Confidence 0.26 Published 2003 Journal Dig. Dis. Sci. Section Abstract Doc Link 14714609 Disease Relevance 0.56 Pain Relevance 0.09
Furthermore, we investigated the role of prostaglandin E2 (PGE2), which is suggested to play major roles in acute inflammation of the stomatch, on uPA and uPAR expression in gastric fibroblasts.
Regulation (roles) of Gene_expression (expression) of uPAR in fibroblasts associated with inflammation
4) Confidence 0.26 Published 2003 Journal Dig. Dis. Sci. Section Abstract Doc Link 14714609 Disease Relevance 0.39 Pain Relevance 0.15

General Comments

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