INT106017

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Context Info
Confidence 0.40
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.67
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dbt) transferase activity, transferring acyl groups (Dbt) cytoplasm (Dbt)
Dbt (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 1 92.24 High High
Taxol 1 88.76 High High
Morphine 1 88.48 High High
drug abuse 22 78.00 Quite High
opiate 6 73.92 Quite High
depression 2 66.88 Quite High
Lasting pain 1 50.00 Quite Low
Pain 9 10.00 Low Low
Fibrositis 3 10.00 Low Low
alcohol 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 64 99.24 Very High Very High Very High
Bronchopulmonary Dysplasia 46 98.76 Very High Very High Very High
Suicidal Behaviour 10 92.64 High High
Cancer 1 90.60 High High
Eating Disorder 4 74.32 Quite High
Depression 2 66.88 Quite High
Pain 5 50.00 Quite Low
Emergencies 6 49.12 Quite Low
Myalgia 1 39.52 Quite Low
Recurrence 8 37.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
APL correlated positively with time for patient 2 with no correlation for patient 3 (both had increased DBT) after 6 months.
Positive_regulation (increased) of DBT
1) Confidence 0.40 Published 2002 Journal Electromyogr Clin Neurophysiol Section Body Doc Link 12395614 Disease Relevance 0 Pain Relevance 0
To date, nine published randomized controlled trials (RCTs) conducted across five research institutions have evaluated DBT.
Positive_regulation (evaluated) of DBT
2) Confidence 0.32 Published 2008 Journal Addiction Science & Clinical Practice Section Body Doc Link PMC2797106 Disease Relevance 0.87 Pain Relevance 0.07
To date, no clinical trials have evaluated DBT for patients with SUD but not BPD.
Positive_regulation (evaluated) of DBT associated with drug dependence and bronchopulmonary dysplasia
3) Confidence 0.32 Published 2008 Journal Addiction Science & Clinical Practice Section Body Doc Link PMC2797106 Disease Relevance 0.71 Pain Relevance 0.14
Despite low sequence identity, the two-domain structure of vinorine synthase shows surprising similarity with structures of several CoA-dependent acyltransferases such as dihydrolipoyl transacetylase, polyketide-associated protein A5, and carnitine acetyltransferase.
Positive_regulation (structures) of dihydrolipoyl transacetylase
4) Confidence 0.00 Published 2005 Journal J. Biol. Chem. Section Abstract Doc Link 15665331 Disease Relevance 0.09 Pain Relevance 0.18

General Comments

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