INT106070

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Context Info
Confidence 0.13
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (TH) small molecule metabolic process (TH) cytoplasm (TH)
signal transducer activity (Oprl1) cytosol (TH) pigmentation (TH)
Anatomy Link Frequency
brain 2
Oprl1 (Rattus norvegicus)
TH (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 10 95.20 Very High Very High Very High
Ventral tegmentum 1 84.04 Quite High
Locus ceruleus 1 82.60 Quite High
Catecholamine 2 80.48 Quite High
orphanin 4 75.00 Quite High
withdrawal 1 69.48 Quite High
analgesia 2 67.04 Quite High
Opioid 2 64.96 Quite High
Pain 1 61.32 Quite High
opioid receptor 1 58.92 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 90.52 High High
Pain 1 61.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic activation of mu, but not ORL1, receptors upregulated TH levels in these cells as previously reported in rat brain.
Positive_regulation (activation) of ORL1 in brain Positive_regulation (upregulated) of TH
1) Confidence 0.13 Published 2002 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12399106 Disease Relevance 0.15 Pain Relevance 1.36

General Comments

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