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Context Info
Confidence 0.12
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK3) mitochondrion (MAPK3) Golgi apparatus (MAPK3)
protein complex assembly (MAPK3) protein complex (MAPK3) cytoplasm (MAPK3)
Oprl1 (Rattus norvegicus)
MAPK3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 10 95.04 Very High Very High Very High
Ventral tegmentum 1 89.88 High High
Locus ceruleus 1 88.44 High High
Catecholamine 2 86.32 High High
withdrawal 1 75.32 Quite High
orphanin 4 75.00 Quite High
analgesia 2 72.88 Quite High
Opioid 2 70.80 Quite High
Pain 1 67.16 Quite High
opioid receptor 1 64.76 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 96.36 Very High Very High Very High
Pain 1 67.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of mu or ORL1 receptors in these cells in turn activates extracellular signal-regulated protein kinases (ERKs), ERK1 and ERK2.
Positive_regulation (Activation) of ORL1 Positive_regulation (activates) of ERK1
1) Confidence 0.12 Published 2002 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12399106 Disease Relevance 0.16 Pain Relevance 1.34

General Comments

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