INT106073

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Context Info
Confidence 0.41
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B, NFKB1) signal transduction (IL1B, NFKB1) nucleoplasm (NFKB1)
mitochondrion (NFKB1) aging (IL1B) cytoplasm (NFKB1)
IL1B (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Abeta 2 98.52 Very High Very High Very High
cytokine 2 97.00 Very High Very High Very High
Inflammation 2 87.96 High High
aspirin 1 74.72 Quite High
cINOD 2 74.00 Quite High
Inflammatory response 1 63.32 Quite High
Disease Link Frequency Relevance Heat
Disease 4 95.60 Very High Very High Very High
Amyloid Plaque 1 94.16 High High
INFLAMMATION 4 87.96 High High
Disease Progression 1 79.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we demonstrate that IL-1beta induces alpha(2)M synthesis/release from a human astroglial cell line (U373) via the activation of the nuclear transcription factor NF-kappaB.
IL-1beta Positive_regulation (induces) of Positive_regulation (activation) of NF-kappaB
1) Confidence 0.41 Published 2002 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12399113 Disease Relevance 0.70 Pain Relevance 0.47

General Comments

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