INT106227

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Context Info
Confidence 0.42
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.13
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (STK11) mitochondrion (STK11) small molecule metabolic process (STK11)
nucleus (STK11) cell cycle (STK11) protein complex (STK11)
Anatomy Link Frequency
pancreas 1
STK11 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 3 89.56 High High
shoulder pain 1 83.40 Quite High
agonist 6 5.00 Very Low Very Low Very Low
Nicotine 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 10 100.00 Very High Very High Very High
Cancer 51 98.20 Very High Very High Very High
Hamartoma 1 97.40 Very High Very High Very High
Thrombosis 3 91.96 High High
Neointima 21 91.24 High High
Metastasis 4 90.52 High High
Cardiovascular Disease 6 90.12 High High
Adenocarcinoma 6 87.36 High High
Pressure And Volume Under Development 1 83.92 Quite High
Shoulder Pain 1 83.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PJS is known to be associated with increased risk of malignancies, especially in the gastrointestinal tract, breast, genitals and pancreas.
PJS Binding (associated) of in pancreas associated with syndrome
1) Confidence 0.42 Published 2002 Journal Jpn. J. Clin. Oncol. Section Abstract Doc Link 12411569 Disease Relevance 1.36 Pain Relevance 0.08
, a target of LKB1, and TSC2, another potential
LKB1 Binding (target) of
2) Confidence 0.13 Published 2008 Journal PPAR Research Section Body Doc Link PMC2515882 Disease Relevance 0.37 Pain Relevance 0.04
PJS is also associated with a 15-fold increased risk of developing cancer and a functional loss of serine/threonine kinase LKB1.
PJS Binding (associated) of associated with cancer and syndrome
3) Confidence 0.01 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC3008825 Disease Relevance 1.40 Pain Relevance 0

General Comments

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