INT106247

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Context Info
Confidence 0.54
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (CCR5, CCL4) endosome (CCR5) cytoplasm (CCR5)
signal transducer activity (CCR5) extracellular space (CCL4) signal transduction (CCL4)
CCR5 (Homo sapiens)
CCL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 99.74 Very High Very High Very High
Morphine 3 99.50 Very High Very High Very High
chemokine 3 86.96 High High
opioid receptor 4 85.40 High High
Opioid 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 58.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional studies revealed that a combination treatment of cells with morphine, an agonist for mu, and MIP-1beta, a ligand for CCR5, suppresses the inhibitory effect of MIP-1beta and increases the stimulatory effect of morphine on CCR5 expression.
CCR5 Binding (ligand) of MIP-1beta associated with agonist and morphine
1) Confidence 0.54 Published 2002 Journal Exp. Cell Res. Section Abstract Doc Link 12413885 Disease Relevance 0.06 Pain Relevance 0.64

General Comments

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