INT10625

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Context Info
Confidence 0.44
First Reported 1984
Last Reported 1992
Negated 3
Speculated 3
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 1.06
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp) extracellular space (Avp) extracellular region (Avp)
response to stress (Avp) signal transducer activity (Avp)
Anatomy Link Frequency
Plasma 2
cardiovascular system 2
cerebrospinal fluid 2
collecting tubules 2
POST 2
Avp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 5 100.00 Very High Very High Very High
agonist 4 100.00 Very High Very High Very High
opiate 2 100.00 Very High Very High Very High
antagonist 1 100.00 Very High Very High Very High
Nicotine 4 97.12 Very High Very High Very High
cva 7 91.04 High High
Opioid 1 90.80 High High
lidocaine 1 87.08 High High
noradrenaline 2 82.08 Quite High
Endogenous opioid 1 78.00 Quite High
Disease Link Frequency Relevance Heat
Diabetes Insipidus 6 99.40 Very High Very High Very High
Hypertension 1 97.72 Very High Very High Very High
Cv General 3 Under Development 4 91.04 High High
Hemorrhage 1 80.80 Quite High
Volume Depletion And Dehydration 1 80.32 Quite High
Sprains And Strains 1 69.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results indicate that TOT deafferentations resulted in significant increases in CRH mRNA expression in the PVN, and a slight but noticeable induction of AVP mRNA in the medial parvocellular but not posterior magnocellular divisions of the PVN.
Regulation (resulted) of Positive_regulation (induction) of AVP in PVN
1) Confidence 0.44 Published 1990 Journal Endocrinology Section Abstract Doc Link 2171915 Disease Relevance 0 Pain Relevance 0
POST lesions did not produce a clear induction in either CRH or AVP mRNA.
Neg (not) Regulation (produce) of Spec (clear) Positive_regulation (induction) of AVP in POST
2) Confidence 0.44 Published 1990 Journal Endocrinology Section Abstract Doc Link 2171915 Disease Relevance 0 Pain Relevance 0
A microradioimmunoassay for cAMP was developed in order to analyse the effects of alpha-adrenergic agonists on vasopressin (AVP)-induced cAMP cell accumulation in single pieces of microdissected medullary (MCT) and cortical (CCT) rat collecting tubules.
Spec (analyse) Regulation (effects) of Spec (analyse) Positive_regulation (accumulation) of AVP in collecting tubules associated with agonist
3) Confidence 0.27 Published 1984 Journal Mol. Cell. Endocrinol. Section Abstract Doc Link 6149967 Disease Relevance 0 Pain Relevance 0.09
Using male Sprague-Dawley rats, we therefore investigated the effect of an opiate receptor antagonist, naloxone (5 mg/kg s.c.), on the plasma concentrations of oxytocin and vasopressin elevated by various pharmacologic stimuli, including histamine (10 mg/kg i.p.), nicotine (0.15 or 1.5 mg/kg i.p.), isoproterenol (30 or 120 micrograms/kg i.m.) and increased [NaCl] in cerebrospinal fluid (CSF; 10 microliter artificial CSF containing 1 M NaCl i.v.t.).
Spec (investigated) Regulation (effect) of Positive_regulation (elevated) of vasopressin in cerebrospinal fluid associated with nicotine, antagonist, narcan and opiate
4) Confidence 0.24 Published 1986 Journal Neuroendocrinology Section Abstract Doc Link 3796791 Disease Relevance 0.16 Pain Relevance 0.63
These results show that the insertion of an extracorporeal circulation into an anaesthetized BDI or LE rat does not adversely affect the cardiovascular system despite the increase in baseline plasma vasopressin concentration in normal rats, and its subsequent removal provides an additional equilibrated blood sample for multiple hormone assay within the same animal.
Neg (not) Regulation (affect) of Positive_regulation (increase) of vasopressin in cardiovascular system associated with diabetes insipidus
5) Confidence 0.24 Published 1990 Journal Pflugers Arch. Section Abstract Doc Link 2293200 Disease Relevance 0.80 Pain Relevance 0.24
Plasma levels of vasopressin (VP), which were also elevated in control rats 1 h after NTS lesions, were not significantly altered in SAD rats.
Neg (not) Regulation (altered) of Positive_regulation (elevated) of vasopressin in Plasma
6) Confidence 0.17 Published 1992 Journal Am. J. Physiol. Section Abstract Doc Link 1510167 Disease Relevance 0.10 Pain Relevance 0.09

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