INT106263

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Context Info
Confidence 0.44
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 9.36
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 2
N1-S1 1
endothelium 1
nodules 1
R3hcc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain management 2 94.40 High High
palliative 2 94.32 High High
Morphine 3 90.16 High High
Opioid 18 88.12 High High
aspirin 3 75.00 Quite High
abdominal pain 3 72.00 Quite High
tramadol 2 66.96 Quite High
tolerance 17 60.24 Quite High
methotrexate 5 56.24 Quite High
cINOD 1 50.04 Quite High
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 448 100.00 Very High Very High Very High
Disease 13 99.66 Very High Very High Very High
Adhesions 12 98.88 Very High Very High Very High
Cirrhosis 14 97.64 Very High Very High Very High
Cancer 463 96.68 Very High Very High Very High
Pain 12 94.40 High High
Recurrence 8 92.36 High High
Metastasis 22 91.48 High High
Pancreatitis 36 90.36 High High
Necrosis 5 84.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quite recently, we performed a "one shot" PEI (a total dose of 50 ml) into two HCC nodules of 4,6 and 3,1 cm respectively, in a patient with Child A cirrhosis.
Gene_expression (nodules) of HCC in nodules associated with cirrhosis and hepatocellular cancer
1) Confidence 0.44 Published 2008 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2531081 Disease Relevance 0.94 Pain Relevance 0.61
Radiofrequency ablation therapy and percutaneous ethanol injection therapy are also used as curative treatments for HCC.5 Because HCC is frequently diagnosed at the intermediate or advanced stages, transarterial chemoembolization (TACE), the most popular nonsurgical alternative, is often used as a palliative treatment,6,7 however, effective only in limited occasion.
Gene_expression (diagnosed) of HCC associated with hepatocellular cancer and palliative
2) Confidence 0.30 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768232 Disease Relevance 1.36 Pain Relevance 0.09
Firstly, we found over-expression of TOP2A in N1-S1 HCC both in the protein and the histology levels.
Gene_expression (expression) of HCC in N1-S1 associated with hepatocellular cancer
3) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2918526 Disease Relevance 1.15 Pain Relevance 0.06
Short-term and low-dose epirubicin chemotherapy led to stable disease in rats bearing established HCC
Gene_expression (established) of HCC associated with hepatocellular cancer and disease
4) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2918526 Disease Relevance 1.15 Pain Relevance 0
The ultrasound-measured HCC size highly correlated with the caliper measurement, plasma GOT level, and CT-measured tumor size
Gene_expression (size) of HCC in plasma associated with cancer and hepatocellular cancer
5) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2918526 Disease Relevance 1.11 Pain Relevance 0
The biochemical parameters in blood samples from HCC-bearing rats were determined to investigate the relationship between US-measured HCC sizes and plasma GOT/GPT levels.
Gene_expression (sizes) of HCC in plasma associated with hepatocellular cancer
6) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2918526 Disease Relevance 1.15 Pain Relevance 0
These findings strongly supported the fidelity of US-based monitoring of HCC progression in rats.


Gene_expression (progression) of HCC associated with hepatocellular cancer
7) Confidence 0.23 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2918526 Disease Relevance 1.14 Pain Relevance 0
However, expression in HCC of mRNAs for intercellular adhesion molecule-1 and vascular cell adhesion molecule-1, both of which are considered to play key roles in attachment of cancer cells to the endothelium, was significantly suppressed by ASP.
Gene_expression (expression) of HCC in endothelium associated with cancer, hepatocellular cancer and adhesions
8) Confidence 0.11 Published 2002 Journal Jpn. J. Cancer Res. Section Abstract Doc Link 12417048 Disease Relevance 1.37 Pain Relevance 0.11

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