INT106271

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Context Info
Confidence 0.25
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Syt1) cytoplasm (Syt1)
Syt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 3 93.60 High High
Migraine 1 87.36 High High
Multiple sclerosis 2 86.84 High High
Disease Link Frequency Relevance Heat
Headache 1 87.36 High High
Demyelinating Disease 2 86.84 High High
Disease 2 80.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Investigating the molecular mechanisms by which parthenolide prevents iNOS/NO synthesis, we found that parthenolide inhibits the activation of p42/44 mitogen-activated protein kinase (MAPK), but not IkBalpha (IkappaBalpha) degradation or nuclear factor-kappaB (NF-kappaB) p65 activation.
Negative_regulation (inhibits) of Neg (not) Positive_regulation (activation) of p65
1) Confidence 0.25 Published 2002 Journal J. Neuroimmunol. Section Abstract Doc Link 12417429 Disease Relevance 0.34 Pain Relevance 0.30

General Comments

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