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Context Info
Confidence 0.38
First Reported 2002
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 7.45
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CEACAM7)
Anatomy Link Frequency
visceral 1
colon 1
bowel 1
lung 1
CEACAM7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 91.76 High High
abdominal pain 3 81.56 Quite High
palliative 2 77.96 Quite High
pain flank 1 67.64 Quite High
Inflammation 15 55.56 Quite High
aspirin 5 50.00 Quite Low
agonist 17 16.12 Low Low
COX2 2 10.00 Low Low
imagery 12 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 56 98.64 Very High Very High Very High
Malignant Neoplastic Disease 17 98.60 Very High Very High Very High
Diarrhoea 5 98.36 Very High Very High Very High
Recurrence 6 98.28 Very High Very High Very High
Lung Cancer 7 98.20 Very High Very High Very High
Metastasis 19 98.12 Very High Very High Very High
Body Weight 2 97.34 Very High Very High Very High
Weight Loss 3 96.72 Very High Very High Very High
Cancer 157 96.56 Very High Very High Very High
Iron-deficiency Anemia 74 94.90 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CEA had transiently decreased postoperatively, but then increased with lung metastases, apparently related to the state of cancer.
Negative_regulation (decreased) of CEA in lung associated with cancer and metastasis
1) Confidence 0.38 Published 2003 Journal Hinyokika Kiyo Section Abstract Doc Link 12696186 Disease Relevance 0.97 Pain Relevance 0.07
After chemoradiotherapy, the CEA level was remarkably decreased.
Negative_regulation (decreased) of CEA
2) Confidence 0.38 Published 2008 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 18633265 Disease Relevance 0.84 Pain Relevance 0.24
As a result, the size the of metastatic lesions markedly reduced and CEA was decreased to the normal level.
Negative_regulation (decreased) of CEA
3) Confidence 0.31 Published 2007 Journal Nippon Shokakibyo Gakkai Zasshi Section Abstract Doc Link 17827908 Disease Relevance 1.81 Pain Relevance 0.08
An increasing CEA level predicted relapse and correlated well with visceral involvement and clinical responses correlated with declining levels of CEA.
Negative_regulation (declining) of CEA in visceral associated with recurrence
4) Confidence 0.19 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1999497 Disease Relevance 0.87 Pain Relevance 0.03
Decreased CEA content and CD44v6 expression and elevated nm23 expression may contribute to the effect of ASA on invasive potential of SW480 colon cancer cells.

Negative_regulation (Decreased) of CEA in colon
5) Confidence 0.17 Published 2002 Journal Eur. J. Clin. Invest. Section Body Doc Link 12423325 Disease Relevance 0 Pain Relevance 0
with elevated serum levels of CEA and/or CA27.29 at the onset of the study,
Negative_regulation (levels) of CEA
6) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 1.06 Pain Relevance 0
Calretinin and CK5/6 were positive, and CEA, S-100 protein, c-kit and CD34 were negative, result in confirmation of a diagnosis of malignant mesothelioma.
Negative_regulation (result) of CEA associated with malignant neoplastic disease and lung cancer
7) Confidence 0.09 Published 2009 Journal Nippon Shokakibyo Gakkai Zasshi Section Abstract Doc Link 19346724 Disease Relevance 0.59 Pain Relevance 0.08
The risk factors for finding GI lesions causing IDA were as follows: male gender (p= 0.004), advanced age (> 50 years) (p= 0.010), weight loss (over 20% of total body weight lost in last 6 month) (p= 0.020), chronic diarrhea (p= 0.006), change of bowel habits (p= 0.043), epigastric tenderness (p= 0.037), raised carcinoembryonic antigen (CEA) level (normal range: 0-7 ng/mL) (p= 0.039), < 10 gr/dl hemoglobin (Hb) level (p=0.054).
Negative_regulation (raised) of CEA in bowel associated with diarrhoea, body weight, weight loss and iron-deficiency anemia
8) Confidence 0.04 Published 2011 Journal International Journal of Medical Sciences Section Abstract Doc Link PMC3014590 Disease Relevance 1.30 Pain Relevance 0

General Comments

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