INT106411

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Context Info
Confidence 0.67
First Reported 2002
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

sulfur compound metabolic process (Sult4a1) cytoplasm (Sult4a1)
Anatomy Link Frequency
dura mater 1
Sult4a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
orphanin 4 100.00 Very High Very High Very High
antagonist 2 100.00 Very High Very High Very High
Antinociceptive 4 50.00 Quite Low
Migraine 1 25.00 Low Low
Pain 2 10.00 Low Low
nMDA receptor 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 7 99.12 Very High Very High Very High
Neuropathic Pain 2 64.12 Quite High
Nociception 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: These results demonstrate that NST produces a biphasic dose-dependent effect on neuropathic pain.
Gene_expression (produces) of NST
1) Confidence 0.67 Published 2004 Journal Anesthesiology Section Body Doc Link 15329601 Disease Relevance 0.06 Pain Relevance 0
The effects of the ORL-1 (NOP(1)) receptor ligand nociceptin (N/OFQ) and the nociceptin antagonists [Nphe(1)]N/OFQ-(1-13)-NH(2) (Nphe) and nocistatin (NST) on neurogenic dural vasodilatation (NDV) in the rat dura mater evoked by electrical stimulation of a closed cranial window were studied.
Gene_expression (effects) of NST in dura mater associated with antagonist, orphanin and increased venous pressure under development
2) Confidence 0.48 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 12423668 Disease Relevance 0.40 Pain Relevance 0.23

General Comments

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