INT106438

Context Info Confidence 0.53 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

mitochondrion (DECR1, PHB2) nucleus (DECR1, PHB2) cytoplasm (DECR1, PHB2) small molecule metabolic process (DECR1) nucleolus (DECR1)

Anatomy Link Frequency coronary artery 2 DECR1 (Homo sapiens) PHB2 (Homo sapiens)

Pain Link Frequency Relevance Heat Angina 1 50.00

Disease Link Frequency Relevance Heat Cv General 3 Under Development 1 50.00 Increased Venous Pressure Under Development 1 5.00 Coronary Artery Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CONCLUSIONS: ROS generated by p22(phox)-based NADH/NADPH oxidase likely mediate the oxidative modification of LDL and might play a major role in pathogenesis of atherosclerotic coronary artery disease.

NADPH Positive_regulation (generated) of Positive_regulation (-based) of p22 in coronary artery

1) Confidence 0.53 Published 2002 Journal Arterioscler. Thromb. Vasc. Biol. Section Body Doc Link 12426213 Disease Relevance 0 Pain Relevance 0

General Comments

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