INT106464

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Context Info
Confidence 0.06
First Reported 2002
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP1) extracellular region (MMP1) proteinaceous extracellular matrix (MMP1)
DNA binding (STK16) cytoplasm (STK16)
STK16 (Homo sapiens)
MMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 8 50.00 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rupture 2 50.08 Quite High
Tendinopathy 1 50.00 Quite Low
Pain 2 49.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, ciprofloxacin and norfloxacin increased basal and IL-1beta-stimulated MMP-1 mRNA expression.
IL-1beta-stimulated Positive_regulation (stimulated) of Gene_expression (expression) of MMP-1
1) Confidence 0.06 Published 2005 Journal Rheumatology (Oxford) Section Body Doc Link 16148020 Disease Relevance 0 Pain Relevance 0
Ciprofloxacin also potentiated IL-1beta-stimulated MMP-1 mRNA expression, but did not potentiate the output of MMP-1, and had no significant effects on MMP-2 mRNA expression or output.
IL-1beta-stimulated Positive_regulation (stimulated) of Gene_expression (expression) of MMP-1
2) Confidence 0.05 Published 2002 Journal Arthritis Rheum. Section Body Doc Link 12428247 Disease Relevance 0.05 Pain Relevance 0

General Comments

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