INT106505

Context Info Confidence 0.01 First Reported 2002 Last Reported 2002 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 3 Disease Relevance 0.93 Pain Relevance 0.39

endoplasmic reticulum (Ptgds, Ptgs2) cytoplasm (Ptgds, Ptgs2) nucleus (Ptgds, Ptgs2) isomerase activity (Ptgds) transport (Ptgds) Golgi apparatus (Ptgds)

Ptgds (Mus musculus) Ptgs2 (Mus musculus)

Pain Link Frequency Relevance Heat Pain 3 87.36 Central nervous system 3 85.28

Disease Link Frequency Relevance Heat Hypersensitivity 3 92.32 Pain 3 87.36 Targeted Disruption 6 68.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PGD synthase (PGDS) catalyzes the isomerization of PGH2 to PGD2 in the presence of sulfhydryl compounds.

PGD2 Binding (isomerization) of PGH2

1) Confidence 0.01 Published 2002 Journal Prostaglandins Other Lipid Mediat. Section Abstract Doc Link 12432930 Disease Relevance 0.31 Pain Relevance 0.13

PGD synthase (PGDS) catalyzes the isomerization of PGH2 to PGD2 in the presence of sulfhydryl compounds.

PGDS Binding (isomerization) of PGH2

2) Confidence 0.01 Published 2002 Journal Prostaglandins Other Lipid Mediat. Section Abstract Doc Link 12432930 Disease Relevance 0.31 Pain Relevance 0.13

PGD synthase (PGDS) catalyzes the isomerization of PGH2 to PGD2 in the presence of sulfhydryl compounds.

PGD synthase Binding (isomerization) of PGH2

3) Confidence 0.01 Published 2002 Journal Prostaglandins Other Lipid Mediat. Section Abstract Doc Link 12432930 Disease Relevance 0.31 Pain Relevance 0.13

General Comments

This test has worked.