INT106573

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Context Info
Confidence 0.43
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pfkm) kinase activity (Pfkm) cytoplasm (Pfkm)
Pfkm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 3 98.68 Very High Very High Very High
Kinase C 3 97.78 Very High Very High Very High
Serotonin 2 87.56 High High
sSRI 2 85.08 High High
antidepressant 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Stress 1 98.06 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Protein kinase C (PKC)-delta, PKC-gamma, stress-activated protein kinase, cAMP-dependent protein kinase beta isoform, Janus protein kinase, and phosphofructokinase M were all down regulated chronically with citalopram and fluoxetine, but not with acute fluoxetine.
Neg (not) Phosphorylation (regulated) of phosphofructokinase M associated with stress, kinase c and fluoxetine
1) Confidence 0.43 Published 2002 Journal Neurosci. Lett. Section Abstract Doc Link 12435479 Disease Relevance 0.10 Pain Relevance 0.64

General Comments

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