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Context Info
Confidence 0.03
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.70

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mitochondrion (IFI27) nucleus (ZNF398) intracellular (ZNF398)
molecular_function (IFI27) DNA binding (ZNF398)
ZNF398 (Homo sapiens)
IFI27 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 9 89.04 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 75.00 Quite High
Lung Cancer 1 69.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro degradation experiments showed that p27(Kip1) degradation was inhibited by NS398, and the addition of purified 26S proteasome reversed this inhibitory effect.
NS398 Negative_regulation (inhibited) of Protein_catabolism (degradation) of p27
1) Confidence 0.03 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 12435820 Disease Relevance 0.21 Pain Relevance 0.70

General Comments

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