INT10669

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Context Info
Confidence 0.57
First Reported 1984
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.36
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Fen1) mitochondrion (Fen1) nucleolus (Fen1)
nucleus (Fen1) DNA binding (Fen1)
Anatomy Link Frequency
FEN 1
Fen1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 6 100.00 Very High Very High Very High
fluoxetine 7 97.60 Very High Very High Very High
cocaine 7 97.44 Very High Very High Very High
addiction 2 96.40 Very High Very High Very High
dexamethasone 1 92.00 High High
alcohol 1 88.84 High High
Serotonin 3 87.32 High High
Potency 1 64.64 Quite High
Morphine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Recurrence 2 98.72 Very High Very High Very High
Drug Dependence 2 96.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo microdialysis experiments demonstrate that these agents preferentially release mesolimbic DA (PHEN) and 5-HT (FEN).
Localization (release) of FEN in FEN associated with dopamine
1) Confidence 0.57 Published 1998 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 9668665 Disease Relevance 0.36 Pain Relevance 0.65
This result supports the view that the 5-HT releasing properties of FEN are mediated by the 5-HT uptake transporter.
Localization (releasing) of FEN
2) Confidence 0.51 Published 1992 Journal Brain Res. Section Abstract Doc Link 1511330 Disease Relevance 0 Pain Relevance 0.51
Thus, despite their structural and pharmacological similarities, FEN, PCA and PFA each act differently to stimulate corticosterone secretion.
Localization (secretion) of FEN
3) Confidence 0.43 Published 1984 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 6323674 Disease Relevance 0 Pain Relevance 0.27

General Comments

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