INT10671

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Context Info
Confidence 0.53
First Reported 1992
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 6.29
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CRX)
Anatomy Link Frequency
spinal 1
fat 1
CRX (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 24 99.00 Very High Very High Very High
Pain 8 96.96 Very High Very High Very High
agonist 1 95.20 Very High Very High Very High
tail-flick 12 95.00 High High
Cannabinoid receptor 1 94.48 High High
intrathecal 3 88.52 High High
narcan 1 87.24 High High
Hyperalgesia 2 85.92 High High
Antihyperalgesic 1 78.16 Quite High
nud 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 270 100.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

28 100.00 Very High Very High Very High
Cirrhosis 6 99.80 Very High Very High Very High
Hypolipidemia 84 99.32 Very High Very High Very High
Cystic Fibrosis 21 99.00 Very High Very High Very High
Gallstones 9 97.64 Very High Very High Very High
Pain 5 96.96 Very High Very High Very High
Syndrome 6 96.52 Very High Very High Very High
Hepatomegaly 12 92.92 High High
Steatorrhea 12 90.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVES: To develop a protocol of controlled CRD in the conscious horse and to evaluate the effect of i.v. xylazine or intrarectal lidocaine on CRD threshold and rectal compliance.
Regulation (controlled) of CRD
1) Confidence 0.53 Published 2005 Journal Equine Vet. J. Section Body Doc Link 15651738 Disease Relevance 0 Pain Relevance 0
Bilateral transections of the spinal dorsolateral funiculi (DLF) did not affect the inhibitory effect of CRD in 4/7 rats and attenuated the inhibitory effect of CRD in the other 3 rats.
Neg (not) Regulation (affect) of CRD in spinal
2) Confidence 0.12 Published 1992 Journal Brain Res. Section Abstract Doc Link 1511335 Disease Relevance 0.07 Pain Relevance 0.53
Vitamin E is the most affected among the liposoluble vitamins in CRD, because its transport is highly dependent on apo B-containing lipoproteins [40].
Regulation (affected) of CRD associated with disorder of lipid metabolism
3) Confidence 0.06 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2956717 Disease Relevance 1.17 Pain Relevance 0
However, the mechanism responsible for fat malabsorption in CRD concerns the absorptive phase as opposed to the digestive phase in CF and cholestatic syndromes.
Regulation (responsible) of CRD in fat associated with fibrosis, syndrome and disorder of lipid metabolism
4) Confidence 0.06 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2956717 Disease Relevance 1.40 Pain Relevance 0.39
A moderate degree of macrovesicular steatosis was previously reported [22,27], but, to our knowledge, no case of cirrhosis has been reported in CRD, in contrast to ABL and HBL [31-33].
Regulation (reported) of CRD associated with hypolipidemia, cirrhosis and disorder of lipid metabolism
5) Confidence 0.06 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2956717 Disease Relevance 1.59 Pain Relevance 0
At 3 micromol/kg, NGV-1, did not affect the pressure-volume relationship during CRD, indicating that TRPV1 channels do not modulate colonic compliance.
Neg (not) Regulation (affect) of CRD
6) Confidence 0.01 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19344705 Disease Relevance 0.37 Pain Relevance 0.86

General Comments

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