INT106758

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Context Info
Confidence 0.18
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.30
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Dusp1) nucleus (Dusp1) cell cycle (Dusp1)
Dusp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 8 89.60 High High
Inflammatory response 2 74.32 Quite High
cINOD 2 67.04 Quite High
Disease Link Frequency Relevance Heat
Vibrio Infection 2 88.40 High High
Autoimmune Disease 2 83.92 Quite High
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, MKP-1 was induced concurrently with the inactivation of JNK and p38, whereas blocking MKP-1 induction by triptolide prevented this inactivation.
Negative_regulation (blocking) of Positive_regulation (induction) of MKP-1
1) Confidence 0.18 Published 2002 Journal J. Immunol. Section Abstract Doc Link 12444149 Disease Relevance 0.13 Pain Relevance 0.15
Induction of MKP-1 by LPS was found to be extracellular signal-regulated kinase dependent and involved enhanced gene expression and increased protein stability.
Negative_regulation (dependent) of Positive_regulation (Induction) of MKP-1
2) Confidence 0.13 Published 2002 Journal J. Immunol. Section Abstract Doc Link 12444149 Disease Relevance 0.17 Pain Relevance 0.22

General Comments

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