INT10677

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Context Info
Confidence 0.24
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 6.20
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (DBI) transport (DBI)
Anatomy Link Frequency
superior 2
DBI (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 7 99.70 Very High Very High Very High
pain pelvic 10 88.72 High High
Inflammation 10 79.48 Quite High
Dopamine 1 55.32 Quite High
methotrexate 5 55.20 Quite High
Analgesic 1 44.44 Quite Low
Pain 1 25.00 Low Low
abdominal pain 10 16.40 Low Low
imagery 7 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ectopic Pregnancy 475 100.00 Very High Very High Very High
Headache 3 99.70 Very High Very High Very High
Emergencies 20 93.44 High High
Tubal Pregnancy 50 90.96 High High
Reprotox - General 1 70 90.08 High High
Reprotox - General 3 10 88.72 High High
Neurodegenerative Disease 30 84.32 Quite High
Appendicitis 10 81.44 Quite High
Chlamydia Infection 10 79.80 Quite High
Missed Abortion 10 74.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In headache sufferers, Ac-beta-EP levels were higher than normal, whereas beta-EP concentrations were lower.
Positive_regulation (higher) of Gene_expression (levels) of beta-EP associated with headache
1) Confidence 0.24 Published 1992 Journal Brain Res. Section Abstract Doc Link 1511339 Disease Relevance 0.30 Pain Relevance 0.33
ROC curves demonstrated significant discriminatory capability of increased CK for EP diagnosis, suggesting that CK concentrations could be used to predict EP.42
Positive_regulation (capability) of Gene_expression (diagnosis) of EP associated with ectopic pregnancy
2) Confidence 0.10 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 1.16 Pain Relevance 0.03
Patients with progesterone levels below 10 ng/ml (31.8 nmol/L) and hCG levels below 1,500 mIU/L are more likely to demonstrate spontaneous resolution of EP.32
Positive_regulation (spontaneous) of Gene_expression (resolution) of EP associated with ectopic pregnancy
3) Confidence 0.09 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 0.88 Pain Relevance 0.12
Serum values of VEGF were significantly increased in EP, and a combination of three independent markers using the formula VEGF/(PAPP-A × Progesterone) was found to be superior to single marker measurements for discrimination between normal intrauterine pregnancy and EP (sensitivity of 97.7% and specificity of 92.4%).13

CREATINE KINASE (CK)

Positive_regulation (measurements) of Gene_expression (sensitivity) of EP in superior associated with ectopic pregnancy
4) Confidence 0.09 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 0.79 Pain Relevance 0.03
Total serum CK levels were found to be significantly higher in the EP group as compared to the controls (p < 0.001), suggesting that this test might be used as a indicator for EP.27
Positive_regulation (higher) of Gene_expression (group) of EP associated with ectopic pregnancy
5) Confidence 0.09 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 1.41 Pain Relevance 0.07
Total serum CK levels were found to be significantly higher in the EP group as compared to the controls (p < 0.001), suggesting that this test might be used as a indicator for EP.27
Positive_regulation (for) of Gene_expression (group) of EP associated with ectopic pregnancy
6) Confidence 0.09 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 1.44 Pain Relevance 0.07
For example, the differences between the wild type and phenotypes resulting from overexpression of the Bchs protein (EP+) are largely attributable to contrast variations.
Positive_regulation (overexpression) of Gene_expression (overexpression) of EP
7) Confidence 0.04 Published 2008 Journal BioData Min Section Body Doc Link PMC2639580 Disease Relevance 0.22 Pain Relevance 0

General Comments

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