INT106778

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Context Info
Confidence 0.34
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 5
Total Number 5
Disease Relevance 4.30
Pain Relevance 4.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (P2rx6)
Anatomy Link Frequency
trigeminal ganglion 2
peripheral nerve 2
dorsal root ganglion 2
microglia 2
P2rx6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 12 100.00 Very High Very High Very High
dorsal root ganglion 1 100.00 Very High Very High Very High
Peripheral nerve injury 9 99.84 Very High Very High Very High
trigeminal ganglion 28 99.68 Very High Very High Very High
Spinal nerve ligature 4 99.04 Very High Very High Very High
Neuropathic pain 8 98.88 Very High Very High Very High
Snapping jaw 9 97.64 Very High Very High Very High
Antinociceptive 2 96.08 Very High Very High Very High
electroacupuncture 7 95.04 Very High Very High Very High
Neurotransmitter 2 93.08 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 35 100.00 Very High Very High Very High
Nervous System Injury 14 99.40 Very High Very High Very High
Neuropathic Pain 12 98.88 Very High Very High Very High
Disease 1 98.60 Very High Very High Very High
Injury 4 98.08 Very High Very High Very High
Nociception 2 97.80 Very High Very High Very High
Temporomandibular Joint Syndrome 9 97.64 Very High Very High Very High
Pain 16 95.36 Very High Very High Very High
Urological Neuroanatomy 4 83.12 Quite High
INFLAMMATION 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we describe the influence of fibronectin on P2X4 receptor expression in microglia and the upregulation of fibronectin after peripheral nerve injury.
Regulation (influence) of Gene_expression (expression) of P2X4 receptor in microglia associated with nervous system injury and peripheral nerve injury
1) Confidence 0.34 Published 2006 Journal Glia Section Abstract Doc Link 16534777 Disease Relevance 0.77 Pain Relevance 0.42
Conversely, the down-regulated P2X3 receptor expression in the lPAG with antisense oligodeoxynucleotide (ODN) for P2X3 gene significantly attenuated the antinociceptive effect of EA treatment.
Regulation (regulated) of Gene_expression (expression) of P2X3 receptor associated with electroacupuncture and antinociceptive
2) Confidence 0.20 Published 2010 Journal Brain Res. Section Abstract Doc Link 20302849 Disease Relevance 1.17 Pain Relevance 1.54
Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats.
Regulation (Changes) of Gene_expression (expression) of P2X3 receptor in trigeminal ganglion associated with ganglion cysts, snapping jaw and trigeminal ganglion
3) Confidence 0.05 Published 2005 Journal Pain Section Title Doc Link 15936887 Disease Relevance 1.18 Pain Relevance 1.23
Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.
Regulation (Alteration) of Gene_expression (expression) of P2X3 receptor in dorsal root ganglion associated with ganglion cysts, pain, dorsal root ganglion and spinal nerve ligature
4) Confidence 0.03 Published 2002 Journal Exp Brain Res Section Title Doc Link 12444483 Disease Relevance 0.44 Pain Relevance 0.66
In sensory ganglia, the differential regulation of P2X3 receptor expression in peripheral nerve injury in intact and injured neurons suggests the existence of cross-excitation [26].
Regulation (regulation) of Gene_expression (expression) of P2X3 receptor in peripheral nerve associated with nervous system injury and peripheral nerve injury
5) Confidence 0.01 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1790972 Disease Relevance 0.74 Pain Relevance 0.53

General Comments

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